Email this article Secretion of Thioredoxin Peroxidase Protein of Cat Liver Fluke Opisthorchis felineus during Modeling of Experimental Opisthorchiasis
- Authors: Petrenko V.A.1, Pakharukova M.Y.1,2, Kovner A.V.1, L’vova M.N.1, Lyakhovich V.V.2, Mordvinov V.A.1,2
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Affiliations:
- Federal Research Centre Institute of Cytology and Genetics of the Siberian Division of the Russian Academy of Sciences
- Research Institute of Molecular Biology and Biophysics
- Issue: Vol 162, No 6 (2017)
- Pages: 773-776
- Section: Microbiology and Immunology
- URL: https://journals.rcsi.science/0007-4888/article/view/238553
- DOI: https://doi.org/10.1007/s10517-017-3710-5
- ID: 238553
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Abstract
Mechanisms of thioredoxin peroxidase secretion by Opisthorchis felineus were studied in vivo and in vitro. Specific antibodies were obtained and used for western blotting and immunohistochemical detection in Syrian hamster model of opisthorchiasis. Secreted thioredoxin peroxidase protein was accumulated in the worm incubation medium under conditions of oxidative stress and in bile duct cells of hamsters with chronic opisthorchiasis.
About the authors
V. A. Petrenko
Federal Research Centre Institute of Cytology and Genetics of the Siberian Division of the Russian Academy of Sciences
Email: pmaria@yandex.ru
Russian Federation, Novosibirsk
M. Yu. Pakharukova
Federal Research Centre Institute of Cytology and Genetics of the Siberian Division of the Russian Academy of Sciences; Research Institute of Molecular Biology and Biophysics
Author for correspondence.
Email: pmaria@yandex.ru
Russian Federation, Novosibirsk; Novosibirsk
A. V. Kovner
Federal Research Centre Institute of Cytology and Genetics of the Siberian Division of the Russian Academy of Sciences
Email: pmaria@yandex.ru
Russian Federation, Novosibirsk
M. N. L’vova
Federal Research Centre Institute of Cytology and Genetics of the Siberian Division of the Russian Academy of Sciences
Email: pmaria@yandex.ru
Russian Federation, Novosibirsk
V. V. Lyakhovich
Research Institute of Molecular Biology and Biophysics
Email: pmaria@yandex.ru
Russian Federation, Novosibirsk
V. A. Mordvinov
Federal Research Centre Institute of Cytology and Genetics of the Siberian Division of the Russian Academy of Sciences; Research Institute of Molecular Biology and Biophysics
Email: pmaria@yandex.ru
Russian Federation, Novosibirsk; Novosibirsk
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