Secretion of Thioredoxin Peroxidase Protein of Cat Liver Fluke Opisthorchis felineus during Modeling of Experimental Opisthorchiasis
- Авторы: Petrenko V.1, Pakharukova M.1,2, Kovner A.1, L’vova M.1, Lyakhovich V.2, Mordvinov V.1,2
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Учреждения:
- Federal Research Centre Institute of Cytology and Genetics of the Siberian Division of the Russian Academy of Sciences
- Research Institute of Molecular Biology and Biophysics
- Выпуск: Том 162, № 6 (2017)
- Страницы: 773-776
- Раздел: Microbiology and Immunology
- URL: https://journals.rcsi.science/0007-4888/article/view/238553
- DOI: https://doi.org/10.1007/s10517-017-3710-5
- ID: 238553
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Аннотация
Mechanisms of thioredoxin peroxidase secretion by Opisthorchis felineus were studied in vivo and in vitro. Specific antibodies were obtained and used for western blotting and immunohistochemical detection in Syrian hamster model of opisthorchiasis. Secreted thioredoxin peroxidase protein was accumulated in the worm incubation medium under conditions of oxidative stress and in bile duct cells of hamsters with chronic opisthorchiasis.
Об авторах
V. Petrenko
Federal Research Centre Institute of Cytology and Genetics of the Siberian Division of the Russian Academy of Sciences
Email: pmaria@yandex.ru
Россия, Novosibirsk
M. Pakharukova
Federal Research Centre Institute of Cytology and Genetics of the Siberian Division of the Russian Academy of Sciences; Research Institute of Molecular Biology and Biophysics
Автор, ответственный за переписку.
Email: pmaria@yandex.ru
Россия, Novosibirsk; Novosibirsk
A. Kovner
Federal Research Centre Institute of Cytology and Genetics of the Siberian Division of the Russian Academy of Sciences
Email: pmaria@yandex.ru
Россия, Novosibirsk
M. L’vova
Federal Research Centre Institute of Cytology and Genetics of the Siberian Division of the Russian Academy of Sciences
Email: pmaria@yandex.ru
Россия, Novosibirsk
V. Lyakhovich
Research Institute of Molecular Biology and Biophysics
Email: pmaria@yandex.ru
Россия, Novosibirsk
V. Mordvinov
Federal Research Centre Institute of Cytology and Genetics of the Siberian Division of the Russian Academy of Sciences; Research Institute of Molecular Biology and Biophysics
Email: pmaria@yandex.ru
Россия, Novosibirsk; Novosibirsk
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