Reconstruction of Ligament and Tendon Defects Using Cell Technologies


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Resumo

We studied the possibility of restoring the integrity of the Achilles tendon in rabbits using autologous multipotent stromal cells. Collagen or gelatin sponges populated with cells were placed in a resorbable Vicryl mesh tube and this tissue-engineered construct was introduced into a defect of the middle part of the Achilles tendon. In 4 months, histological analysis showed complete regeneration of the tendon with the formation of parallel collagen fibers, spindle-shaped tenocytes, and newly formed vessels.

Sobre autores

R. Chailakhyan

N. F. Gamaleya Research Centre of Epidemiology and Microbiology, Ministry of Health of the Russian Federation

Autor responsável pela correspondência
Email: rubenchail@yandex.ru
Rússia, Moscow

A. Shekhter

I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation

Email: rubenchail@yandex.ru
Rússia, Moscow

S. Ivannikov

I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation

Email: rubenchail@yandex.ru
Rússia, Moscow

V. Tel’pukhov

I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation

Email: rubenchail@yandex.ru
Rússia, Moscow

D. Suslin

I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation

Email: rubenchail@yandex.ru
Rússia, Moscow

Yu. Gerasimov

N. F. Gamaleya Research Centre of Epidemiology and Microbiology, Ministry of Health of the Russian Federation

Email: rubenchail@yandex.ru
Rússia, Moscow

A. Tonenkov

I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation

Email: rubenchail@yandex.ru
Rússia, Moscow

A. Grosheva

N. F. Gamaleya Research Centre of Epidemiology and Microbiology, Ministry of Health of the Russian Federation

Email: rubenchail@yandex.ru
Rússia, Moscow

P. Panyushkin

I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation

Email: rubenchail@yandex.ru
Rússia, Moscow

I. Moskvina

N. F. Gamaleya Research Centre of Epidemiology and Microbiology, Ministry of Health of the Russian Federation

Email: rubenchail@yandex.ru
Rússia, Moscow

N. Vorob’eva

Institute of Photonics Technologies, Russian Academy of Sciences, Federal Research Center “Crystallography and Photonics”, Russian Academy of Sciences

Email: rubenchail@yandex.ru
Rússia, Moscow

V. Bagratashvili

Institute of Photonics Technologies, Russian Academy of Sciences, Federal Research Center “Crystallography and Photonics”, Russian Academy of Sciences

Email: rubenchail@yandex.ru
Rússia, Moscow


Declaração de direitos autorais © Springer Science+Business Media New York, 2017

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