Reconstruction of Ligament and Tendon Defects Using Cell Technologies
- Autores: Chailakhyan R.1, Shekhter A.2, Ivannikov S.2, Tel’pukhov V.2, Suslin D.2, Gerasimov Y.1, Tonenkov A.2, Grosheva A.1, Panyushkin P.2, Moskvina I.1, Vorob’eva N.3, Bagratashvili V.3
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Afiliações:
- N. F. Gamaleya Research Centre of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
- I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
- Institute of Photonics Technologies, Russian Academy of Sciences, Federal Research Center “Crystallography and Photonics”, Russian Academy of Sciences
- Edição: Volume 162, Nº 4 (2017)
- Páginas: 563-568
- Seção: Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)
- URL: https://journals.rcsi.science/0007-4888/article/view/238378
- DOI: https://doi.org/10.1007/s10517-017-3660-y
- ID: 238378
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Resumo
We studied the possibility of restoring the integrity of the Achilles tendon in rabbits using autologous multipotent stromal cells. Collagen or gelatin sponges populated with cells were placed in a resorbable Vicryl mesh tube and this tissue-engineered construct was introduced into a defect of the middle part of the Achilles tendon. In 4 months, histological analysis showed complete regeneration of the tendon with the formation of parallel collagen fibers, spindle-shaped tenocytes, and newly formed vessels.
Sobre autores
R. Chailakhyan
N. F. Gamaleya Research Centre of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Autor responsável pela correspondência
Email: rubenchail@yandex.ru
Rússia, Moscow
A. Shekhter
I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Rússia, Moscow
S. Ivannikov
I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Rússia, Moscow
V. Tel’pukhov
I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Rússia, Moscow
D. Suslin
I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Rússia, Moscow
Yu. Gerasimov
N. F. Gamaleya Research Centre of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Rússia, Moscow
A. Tonenkov
I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Rússia, Moscow
A. Grosheva
N. F. Gamaleya Research Centre of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Rússia, Moscow
P. Panyushkin
I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Rússia, Moscow
I. Moskvina
N. F. Gamaleya Research Centre of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Rússia, Moscow
N. Vorob’eva
Institute of Photonics Technologies, Russian Academy of Sciences, Federal Research Center “Crystallography and Photonics”, Russian Academy of Sciences
Email: rubenchail@yandex.ru
Rússia, Moscow
V. Bagratashvili
Institute of Photonics Technologies, Russian Academy of Sciences, Federal Research Center “Crystallography and Photonics”, Russian Academy of Sciences
Email: rubenchail@yandex.ru
Rússia, Moscow