Effects of Anti-CD206 Antibodies on Macrophage Functions in Male CBF1 Mice with Lipidemia

A. P. Lykov; T. A. Korolenko; L. V. Sakhno; O. V. Poveshchenko; N. A. Bondarenko; M. A. Surovtseva; N. V. Goncharova

doi:10.1007/s10517-016-3584-y

Effects of Anti-CD206 Antibodies on Macrophage Functions in Male CBF1 Mice with Lipidemia

Autores: Lykov A.¹, Korolenko T.², Sakhno L.³, Poveshchenko O.¹, Bondarenko N.¹, Surovtseva M.¹, Goncharova N.²
Afiliações:
1. Research Institute of Clinical and Experimental Lymphology
2. Research Institute of Physiology and Fundamental Medicine
3. Institute of Fundamental and Clinical Immunology
Edição: Volume 162, Nº 2 (2016)
Páginas: 237-239
Seção: Article
URL: https://journals.rcsi.science/0007-4888/article/view/238073
DOI: https://doi.org/10.1007/s10517-016-3584-y
ID: 238073

Citar

Texto integral

Acesso aberto
Acesso é fechado

Acesso está concedido
Acesso é fechado

Somente assinantes

Resumo
Sobre autores
Bibliografia
Estatísticas

Resumo

The effects of anti-CD208 antibodies (mannose receptor) on functional characteristics of peritoneal macrophages were studied in intact mice and mice with lipidemia induced by poloxamer-407. Lipidemia was associated with suppression of phagocytosis and increase in spontaneous proliferative potential and NO production by macrophages. Anti-CD206 antibodies suppressed NO production by macrophages in mice with lipidemia.