Effects of Anti-CD206 Antibodies on Macrophage Functions in Male CBF1 Mice with Lipidemia

A. P. Lykov; T. A. Korolenko; L. V. Sakhno; O. V. Poveshchenko; N. A. Bondarenko; M. A. Surovtseva; N. V. Goncharova

doi:10.1007/s10517-016-3584-y

Effects of Anti-CD206 Antibodies on Macrophage Functions in Male CBF1 Mice with Lipidemia

Авторлар: Lykov A.¹, Korolenko T.², Sakhno L.³, Poveshchenko O.¹, Bondarenko N.¹, Surovtseva M.¹, Goncharova N.²
Мекемелер:
1. Research Institute of Clinical and Experimental Lymphology
2. Research Institute of Physiology and Fundamental Medicine
3. Institute of Fundamental and Clinical Immunology
Шығарылым: Том 162, № 2 (2016)
Беттер: 237-239
Бөлім: Article
URL: https://journals.rcsi.science/0007-4888/article/view/238073
DOI: https://doi.org/10.1007/s10517-016-3584-y
ID: 238073

Дәйексөз келтіру

Толық мәтін

Ашық рұқсат
Рұқсат жабық

Рұқсат берілді
Рұқсат жабық

Тек жазылушылар үшін

Аннотация
Авторлар туралы
Әдебиет тізімі
Статистика

Аннотация

The effects of anti-CD208 antibodies (mannose receptor) on functional characteristics of peritoneal macrophages were studied in intact mice and mice with lipidemia induced by poloxamer-407. Lipidemia was associated with suppression of phagocytosis and increase in spontaneous proliferative potential and NO production by macrophages. Anti-CD206 antibodies suppressed NO production by macrophages in mice with lipidemia.