Enviar artigo por via de e-mail Silicon Nanoparticles as Amplifiers of the Ultrasonic Effect in Sonodynamic Therapy
- Autores: Osminkina L.1, Kudryavtsev A.2, Zinovyev S.3, Sviridov A.1, Kargina Y.1, Tamarov K.1, Nikiforov V.1, Ivanov A.3, Vasilyev A.1,4, Timoshenko V.1
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Afiliações:
- Physical Faculty, M. V. Lomonosov Moscow State University
- Institute of Theoretical and Experimental Biophysics, the Russian Academy of Sciences
- N. N. Blokhin Russian Cancer Research Center
- Ural Federal University
- Edição: Volume 161, Nº 2 (2016)
- Páginas: 296-299
- Seção: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/237347
- DOI: https://doi.org/10.1007/s10517-016-3399-x
- ID: 237347
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Resumo
The possibility of using mesoporous silicon nanoparticles as amplifiers (sensitizers) of therapeutic ultrasonic exposure were studied experimentally in vitro and in vivo. The combination of nanoparticles and ultrasound led to a significant inhibition of Hep-2 cancer cell proliferation and Lewis lung carcinoma growth in mice. These results indicated good prospects of using silicon nanoparticles as sensitizers for sonodynamic therapy of tumors.
Sobre autores
L. Osminkina
Physical Faculty, M. V. Lomonosov Moscow State University
Autor responsável pela correspondência
Email: osminkina@mig.phys.msu.ru
Rússia, Moscow
A. Kudryavtsev
Institute of Theoretical and Experimental Biophysics, the Russian Academy of Sciences
Email: osminkina@mig.phys.msu.ru
Rússia, Pushchino, Moscow Region
S. Zinovyev
N. N. Blokhin Russian Cancer Research Center
Email: osminkina@mig.phys.msu.ru
Rússia, Moscow
A. Sviridov
Physical Faculty, M. V. Lomonosov Moscow State University
Email: osminkina@mig.phys.msu.ru
Rússia, Moscow
Yu. Kargina
Physical Faculty, M. V. Lomonosov Moscow State University
Email: osminkina@mig.phys.msu.ru
Rússia, Moscow
K. Tamarov
Physical Faculty, M. V. Lomonosov Moscow State University
Email: osminkina@mig.phys.msu.ru
Rússia, Moscow
V. Nikiforov
Physical Faculty, M. V. Lomonosov Moscow State University
Email: osminkina@mig.phys.msu.ru
Rússia, Moscow
A. Ivanov
N. N. Blokhin Russian Cancer Research Center
Email: osminkina@mig.phys.msu.ru
Rússia, Moscow
A. Vasilyev
Physical Faculty, M. V. Lomonosov Moscow State University; Ural Federal University
Email: osminkina@mig.phys.msu.ru
Rússia, Moscow; Ekaterinburg
V. Timoshenko
Physical Faculty, M. V. Lomonosov Moscow State University
Email: osminkina@mig.phys.msu.ru
Rússia, Moscow
