Мақаланы E-mail арқылы жіберу Effect of Nanocrystalline Particles of Chitin on Blood Components in Humans and Experimental Animals
- Авторлар: Drozd N.1, Torlopov M.2, Udoratina E.2, Logvinova Y.1
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Мекемелер:
- Hematology Research Center, Ministry of Health of the Russian Federation
- Institute of Chemistry of Komi Research Center, Ural Division of Russian Academy of Science
- Шығарылым: Том 164, № 6 (2018)
- Беттер: 766-769
- Бөлім: Biotechnologies
- URL: https://journals.rcsi.science/0007-4888/article/view/239903
- DOI: https://doi.org/10.1007/s10517-018-4076-z
- ID: 239903
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
Nanocrystalline particles of chitin in the form of hydrosol in a concentration of 0.63 mg/ml have no effect on aggregation of human platelets and clotting time of platelet-poor plasma in coagulation tests. ADP-induced aggregation of human platelets was inhibited by these nanoparticles in concentrations of 0.63 and 1.00 mg/ml in comparison with the control. Intravenous administration of nanoparticles in a dose of 1 mg/kg to guinea pigs produced no anticoagulant effect. The nanocrystalline particles of chitin can be of interest as potential drug delivery systems.
Авторлар туралы
N. Drozd
Hematology Research Center, Ministry of Health of the Russian Federation
Хат алмасуға жауапты Автор.
Email: nndrozd@mail.ru
Ресей, Moscow
M. Torlopov
Institute of Chemistry of Komi Research Center, Ural Division of Russian Academy of Science
Email: nndrozd@mail.ru
Ресей, Syktyvkar, Republic of Komi
E. Udoratina
Institute of Chemistry of Komi Research Center, Ural Division of Russian Academy of Science
Email: nndrozd@mail.ru
Ресей, Syktyvkar, Republic of Komi
Yu. Logvinova
Hematology Research Center, Ministry of Health of the Russian Federation
Email: nndrozd@mail.ru
Ресей, Moscow
