Мақаланы E-mail арқылы жіберу Modeling of Magnetite Nanoparticles Behavior under Conditions of Microcirculation and Analysis of In Vivo Toxicity
- Авторлар: Sakharov D.1,2, Rudakovskaya P.3, Maltseva D.1, Trushkin E.1, Tonevitskaya S.2
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Мекемелер:
- BioClinicum Research and Development Center
- Moscow State University of Mechanical Engineering (MAMI)
- National University of Science and Technology (MISiS)
- Шығарылым: Том 161, № 1 (2016)
- Беттер: 116-119
- Бөлім: Biotechnologies
- URL: https://journals.rcsi.science/0007-4888/article/view/237179
- DOI: https://doi.org/10.1007/s10517-016-3359-5
- ID: 237179
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
The behavior of magnetite nanoparticles was studied in the cell chip microcapillaries. No aggregation of magnetite nanoparticles under conditions of long-term circulation was noted. Biodistribution and toxicity of magnetite nanoparticles (14 nm) and aminated magnetite after their intragastric administration to mice were studied in vivo. According to mass spectrometry and microscopy data, accumulation of nanoparticles occurred mainly in the liver cells.
Авторлар туралы
D. Sakharov
BioClinicum Research and Development Center; Moscow State University of Mechanical Engineering (MAMI)
Хат алмасуға жауапты Автор.
Email: d.sakharov@bioclinicum.com
Ресей, Moscow; Moscow
P. Rudakovskaya
National University of Science and Technology (MISiS)
Email: d.sakharov@bioclinicum.com
Ресей, Moscow
D. Maltseva
BioClinicum Research and Development Center
Email: d.sakharov@bioclinicum.com
Ресей, Moscow
E. Trushkin
BioClinicum Research and Development Center
Email: d.sakharov@bioclinicum.com
Ресей, Moscow
S. Tonevitskaya
Moscow State University of Mechanical Engineering (MAMI)
Email: d.sakharov@bioclinicum.com
Ресей, Moscow
