Email this article Profile of microRNA in Blood Plasma of Healthy Humans
- Authors: Skurnikov M.Y.1,2, Makarova Y.A.1,3, Knyazev E.N.2, Fomicheva K.A.1, Nyushko K.M.1, Saribekyan E.K.1, Alekseev B.Y.1, Kaprin A.D.1
-
Affiliations:
- P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation
- Bioclinicum Research and Engineering Center
- V. A. Engelhard Institute of Molecular Biology, Russian Academy of Sciences
- Issue: Vol 160, No 5 (2016)
- Pages: 632-634
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/236848
- DOI: https://doi.org/10.1007/s10517-016-3235-3
- ID: 236848
Cite item
Open Access
Access granted
Subscription Access
Abstract
Analysis of the plasma microRNA profile can be used for the diagnosis of various pathological and physiological conditions. Complete microRNA microprofiling is an extremely important task. Here we used microarray analysis allowing measurement of the expression of 2500 microRNA (MirBase, version 20). About 10% known microRNA were found in the plasma. Most of the detected microRNA (69 microRNA; ~30%) were encoded by mirtrons.
About the authors
M. Yu. Skurnikov
P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation; Bioclinicum Research and Engineering Center
Author for correspondence.
Email: mshkurnikov@gmail.com
Russian Federation, Moscow; Moscow
Yu. A. Makarova
P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation; V. A. Engelhard Institute of Molecular Biology, Russian Academy of Sciences
Email: mshkurnikov@gmail.com
Russian Federation, Moscow; Moscow
E. N. Knyazev
Bioclinicum Research and Engineering Center
Email: mshkurnikov@gmail.com
Russian Federation, Moscow
K. A. Fomicheva
P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation
Email: mshkurnikov@gmail.com
Russian Federation, Moscow
K. M. Nyushko
P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation
Email: mshkurnikov@gmail.com
Russian Federation, Moscow
E. K. Saribekyan
P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation
Email: mshkurnikov@gmail.com
Russian Federation, Moscow
B. Ya. Alekseev
P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation
Email: mshkurnikov@gmail.com
Russian Federation, Moscow
A. D. Kaprin
P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation
Email: mshkurnikov@gmail.com
Russian Federation, Moscow
Supplementary files
