Profile of microRNA in Blood Plasma of Healthy Humans

M. Yu. Skurnikov; Yu. A. Makarova; E. N. Knyazev; K. A. Fomicheva; K. M. Nyushko; E. K. Saribekyan; B. Ya. Alekseev; A. D. Kaprin

doi:10.1007/s10517-016-3235-3

Profile of microRNA in Blood Plasma of Healthy Humans

作者: Skurnikov M.¹^,2, Makarova Y.¹^,3, Knyazev E.², Fomicheva K.¹, Nyushko K.¹, Saribekyan E.¹, Alekseev B.¹, Kaprin A.¹
隶属关系:
1. P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation
2. Bioclinicum Research and Engineering Center
3. V. A. Engelhard Institute of Molecular Biology, Russian Academy of Sciences
期: 卷 160, 编号 5 (2016)
页面: 632-634
栏目: Article
URL: https://journals.rcsi.science/0007-4888/article/view/236848
DOI: https://doi.org/10.1007/s10517-016-3235-3
ID: 236848

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详细

Analysis of the plasma microRNA profile can be used for the diagnosis of various pathological and physiological conditions. Complete microRNA microprofiling is an extremely important task. Here we used microarray analysis allowing measurement of the expression of 2500 microRNA (MirBase, version 20). About 10% known microRNA were found in the plasma. Most of the detected microRNA (69 microRNA; ~30%) were encoded by mirtrons.

作者简介

M. Skurnikov

P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation; Bioclinicum Research and Engineering Center

编辑信件的主要联系方式.
Email: mshkurnikov@gmail.com
俄罗斯联邦, Moscow; Moscow

Yu. Makarova

P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation; V. A. Engelhard Institute of Molecular Biology, Russian Academy of Sciences

Email: mshkurnikov@gmail.com
俄罗斯联邦, Moscow; Moscow