Email this article Effect of Synthetic Organoselenium Drug on the Degree of Pathological Changes in the Organs of White Mice Immunized with Tularemia and Brucellosis Vaccines
- Authors: Yurieva O.V.1, Dubrovina V.I.1, Potapov V.A.2, Musalov M.V.2, Starovoitova T.P.1, Ivanova T.A.1, Gromova A.V.1, Shkaruba T.T.1, Balakhonov S.V.1
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Affiliations:
- Irkutsk Research Anti-Plague Institute, Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
- A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Division of the Russian Academy of Science
- Issue: Vol 168, No 1 (2019)
- Pages: 66-68
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/242216
- DOI: https://doi.org/10.1007/s10517-019-04648-0
- ID: 242216
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Abstract
We studied the effect of the organoselenium compound 2,6-dipyridinium-9-selenium-bicyclo[ 3,3,1]nonan dibromide (974zh) on the severity of pathological changes in the organs of experimental animals immunized with live tularemia and brucellosis vaccines. It was found that 974zh reduced reactogenicity of vaccines for experimental animals. Our findings indicate the prospects for further studies of the effects of 974zh on the functional state of experimental animals.
About the authors
O. V. Yurieva
Irkutsk Research Anti-Plague Institute, Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Email: dubrovina-valya@mail.ru
Russian Federation, Irkutsk
V. I. Dubrovina
Irkutsk Research Anti-Plague Institute, Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Author for correspondence.
Email: dubrovina-valya@mail.ru
Russian Federation, Irkutsk
V. A. Potapov
A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Division of the Russian Academy of Science
Email: dubrovina-valya@mail.ru
Russian Federation, Irkutsk
M. V. Musalov
A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Division of the Russian Academy of Science
Email: dubrovina-valya@mail.ru
Russian Federation, Irkutsk
T. P. Starovoitova
Irkutsk Research Anti-Plague Institute, Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Email: dubrovina-valya@mail.ru
Russian Federation, Irkutsk
T. A. Ivanova
Irkutsk Research Anti-Plague Institute, Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Email: dubrovina-valya@mail.ru
Russian Federation, Irkutsk
A. V. Gromova
Irkutsk Research Anti-Plague Institute, Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Email: dubrovina-valya@mail.ru
Russian Federation, Irkutsk
T. T. Shkaruba
Irkutsk Research Anti-Plague Institute, Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Email: dubrovina-valya@mail.ru
Russian Federation, Irkutsk
S. V. Balakhonov
Irkutsk Research Anti-Plague Institute, Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Email: dubrovina-valya@mail.ru
Russian Federation, Irkutsk
