Email this article Comparative Effects of Platelet-Rich Plasma, Platelet Lysate, and Fetal Calf Serum on Mesenchymal Stem Cells
- Authors: Lykov A.P.1,2, Bondarenko N.A.1,2, Surovtseva M.A.1,2, Kim I.I.1,2, Poveshchenko O.V.1,2, Pokushalov E.A.1,2, Konenkov V.I.1
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Affiliations:
- Research Institute of Clinical and Experimental Lymphology
- E. N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation
- Issue: Vol 163, No 6 (2017)
- Pages: 757-760
- Section: Immunology and Microbiology
- URL: https://journals.rcsi.science/0007-4888/article/view/239238
- DOI: https://doi.org/10.1007/s10517-017-3897-5
- ID: 239238
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Abstract
We studied the effects of human platelet-rich plasma and platelet lysate on proliferation, migration, and colony-forming properties of rat mesenchymal stem cells. Platelet-rich plasma and platelet lysate stimulated the proliferation, migration, and colony formation of mesenchymal stem cells. A real-time study showed that platelet-rich plasma produces the most potent stimulatory effect, while both platelet-rich plasma and platelet lysate stimulated migration of cells.
About the authors
A. P. Lykov
Research Institute of Clinical and Experimental Lymphology; E. N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation
Author for correspondence.
Email: aplykov2@mail.ru
Russian Federation, Novosibirsk; Novosibirsk
N. A. Bondarenko
Research Institute of Clinical and Experimental Lymphology; E. N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation
Email: aplykov2@mail.ru
Russian Federation, Novosibirsk; Novosibirsk
M. A. Surovtseva
Research Institute of Clinical and Experimental Lymphology; E. N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation
Email: aplykov2@mail.ru
Russian Federation, Novosibirsk; Novosibirsk
I. I. Kim
Research Institute of Clinical and Experimental Lymphology; E. N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation
Email: aplykov2@mail.ru
Russian Federation, Novosibirsk; Novosibirsk
O. V. Poveshchenko
Research Institute of Clinical and Experimental Lymphology; E. N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation
Email: aplykov2@mail.ru
Russian Federation, Novosibirsk; Novosibirsk
E. A. Pokushalov
Research Institute of Clinical and Experimental Lymphology; E. N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation
Email: aplykov2@mail.ru
Russian Federation, Novosibirsk; Novosibirsk
V. I. Konenkov
Research Institute of Clinical and Experimental Lymphology
Email: aplykov2@mail.ru
Russian Federation, Novosibirsk
