Comparative Effects of Platelet-Rich Plasma, Platelet Lysate, and Fetal Calf Serum on Mesenchymal Stem Cells

A. P. Lykov; N. A. Bondarenko; M. A. Surovtseva; I. I. Kim; O. V. Poveshchenko; E. A. Pokushalov; V. I. Konenkov

doi:10.1007/s10517-017-3897-5

Comparative Effects of Platelet-Rich Plasma, Platelet Lysate, and Fetal Calf Serum on Mesenchymal Stem Cells

Autores: Lykov A.¹^,2, Bondarenko N.¹^,2, Surovtseva M.¹^,2, Kim I.¹^,2, Poveshchenko O.¹^,2, Pokushalov E.¹^,2, Konenkov V.¹
Afiliações:
1. Research Institute of Clinical and Experimental Lymphology
2. E. N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation
Edição: Volume 163, Nº 6 (2017)
Páginas: 757-760
Seção: Immunology and Microbiology
URL: https://journals.rcsi.science/0007-4888/article/view/239238
DOI: https://doi.org/10.1007/s10517-017-3897-5
ID: 239238

Citar

Texto integral

Acesso aberto
Acesso é fechado

Acesso está concedido
Acesso é fechado

Somente assinantes

Resumo
Sobre autores
Bibliografia
Estatísticas

Resumo

We studied the effects of human platelet-rich plasma and platelet lysate on proliferation, migration, and colony-forming properties of rat mesenchymal stem cells. Platelet-rich plasma and platelet lysate stimulated the proliferation, migration, and colony formation of mesenchymal stem cells. A real-time study showed that platelet-rich plasma produces the most potent stimulatory effect, while both platelet-rich plasma and platelet lysate stimulated migration of cells.