Comparative Effects of Platelet-Rich Plasma, Platelet Lysate, and Fetal Calf Serum on Mesenchymal Stem Cells

A. P. Lykov; N. A. Bondarenko; M. A. Surovtseva; I. I. Kim; O. V. Poveshchenko; E. A. Pokushalov; V. I. Konenkov

doi:10.1007/s10517-017-3897-5

Comparative Effects of Platelet-Rich Plasma, Platelet Lysate, and Fetal Calf Serum on Mesenchymal Stem Cells

作者: Lykov A.¹^,2, Bondarenko N.¹^,2, Surovtseva M.¹^,2, Kim I.¹^,2, Poveshchenko O.¹^,2, Pokushalov E.¹^,2, Konenkov V.¹
隶属关系:
1. Research Institute of Clinical and Experimental Lymphology
2. E. N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation
期: 卷 163, 编号 6 (2017)
页面: 757-760
栏目: Immunology and Microbiology
URL: https://journals.rcsi.science/0007-4888/article/view/239238
DOI: https://doi.org/10.1007/s10517-017-3897-5
ID: 239238

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We studied the effects of human platelet-rich plasma and platelet lysate on proliferation, migration, and colony-forming properties of rat mesenchymal stem cells. Platelet-rich plasma and platelet lysate stimulated the proliferation, migration, and colony formation of mesenchymal stem cells. A real-time study showed that platelet-rich plasma produces the most potent stimulatory effect, while both platelet-rich plasma and platelet lysate stimulated migration of cells.