电邮这篇文章 Study of Fibronectin Type III-Like Domains Role in Activation of gp130 Receptor
- 作者: Stepanov A.V.1, Rybinets A.S.1, Dronina M.A.1, Deev S.M.1
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隶属关系:
- M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
- 期: 卷 161, 编号 1 (2016)
- 页面: 72-74
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/237109
- DOI: https://doi.org/10.1007/s10517-016-3348-8
- ID: 237109
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详细
Chimeric gp130 receptors were produced to study the role of three fibronectin type III-like domains in activation of gp130 receptor machinery. The ligand-induced dimerization of gp130 was sufficient to trigger STAT3 signaling pathway. These findings can be used as the basis in designing novel therapeutic gp130 inhibitors.
作者简介
A. Stepanov
M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
编辑信件的主要联系方式.
Email: Stepanov.Aleksei.v@gmail.com
俄罗斯联邦, Moscow
A. Rybinets
M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: Stepanov.Aleksei.v@gmail.com
俄罗斯联邦, Moscow
M. Dronina
M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: Stepanov.Aleksei.v@gmail.com
俄罗斯联邦, Moscow
S. Deev
M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: Stepanov.Aleksei.v@gmail.com
俄罗斯联邦, Moscow
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