Effect of Repeated 1-h Episodes of Immobilization Stress on Activity of Glucocorticoid Metabolism Enzymes in the Liver
- Authors: Tseilikman V.E.1, Kozochkin D.A.1, Sinitskii A.I.1, Tseylikman O.B.2, Lapshin M.S.2, Kuzina O.V.1, Komel’kova M.V.1, Telesheva I.B.1
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Affiliations:
- South-Ural State Medical University, the Ministry of health of the Russian Federation
- South-Ural State University (National Research University)
- Issue: Vol 160, No 5 (2016)
- Pages: 614-616
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/236838
- DOI: https://doi.org/10.1007/s10517-016-3230-8
- ID: 236838
Cite item
Abstract
Differences in corticosterone level associated with different activity of glucocorticoid-oxidizing enzymes in the liver were revealed in rats exposed to stress. Pro-inflammatory changes in the liver were associated with enhanced CYP3A-dependent monooxygenation.
About the authors
V. E. Tseilikman
South-Ural State Medical University, the Ministry of health of the Russian Federation
Author for correspondence.
Email: vadimed@yandex.ru
Russian Federation, Chelyabinsk
D. A. Kozochkin
South-Ural State Medical University, the Ministry of health of the Russian Federation
Email: vadimed@yandex.ru
Russian Federation, Chelyabinsk
A. I. Sinitskii
South-Ural State Medical University, the Ministry of health of the Russian Federation
Email: vadimed@yandex.ru
Russian Federation, Chelyabinsk
O. B. Tseylikman
South-Ural State University (National Research University)
Email: vadimed@yandex.ru
Russian Federation, Chelyabinsk
M. S. Lapshin
South-Ural State University (National Research University)
Email: vadimed@yandex.ru
Russian Federation, Chelyabinsk
O. V. Kuzina
South-Ural State Medical University, the Ministry of health of the Russian Federation
Email: vadimed@yandex.ru
Russian Federation, Chelyabinsk
M. V. Komel’kova
South-Ural State Medical University, the Ministry of health of the Russian Federation
Email: vadimed@yandex.ru
Russian Federation, Chelyabinsk
I. B. Telesheva
South-Ural State Medical University, the Ministry of health of the Russian Federation
Email: vadimed@yandex.ru
Russian Federation, Chelyabinsk