Effect of Repeated 1-h Episodes of Immobilization Stress on Activity of Glucocorticoid Metabolism Enzymes in the Liver


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Differences in corticosterone level associated with different activity of glucocorticoid-oxidizing enzymes in the liver were revealed in rats exposed to stress. Pro-inflammatory changes in the liver were associated with enhanced CYP3A-dependent monooxygenation.

作者简介

V. Tseilikman

South-Ural State Medical University, the Ministry of health of the Russian Federation

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Email: vadimed@yandex.ru
俄罗斯联邦, Chelyabinsk

D. Kozochkin

South-Ural State Medical University, the Ministry of health of the Russian Federation

Email: vadimed@yandex.ru
俄罗斯联邦, Chelyabinsk

A. Sinitskii

South-Ural State Medical University, the Ministry of health of the Russian Federation

Email: vadimed@yandex.ru
俄罗斯联邦, Chelyabinsk

O. Tseylikman

South-Ural State University (National Research University)

Email: vadimed@yandex.ru
俄罗斯联邦, Chelyabinsk

M. Lapshin

South-Ural State University (National Research University)

Email: vadimed@yandex.ru
俄罗斯联邦, Chelyabinsk

O. Kuzina

South-Ural State Medical University, the Ministry of health of the Russian Federation

Email: vadimed@yandex.ru
俄罗斯联邦, Chelyabinsk

M. Komel’kova

South-Ural State Medical University, the Ministry of health of the Russian Federation

Email: vadimed@yandex.ru
俄罗斯联邦, Chelyabinsk

I. Telesheva

South-Ural State Medical University, the Ministry of health of the Russian Federation

Email: vadimed@yandex.ru
俄罗斯联邦, Chelyabinsk


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