A Precision Approach to the Diagnosis and Choice of Tactics in the Treatment of Endometrial Hyperplasia in Perimenopause


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Abstract

Abstract—This study was aimed at the identification of the most significant clinical, anatomical, and molecular risk factors of the occurrence and progression of endometrial hyperplastic processes and the development of endometrial malignant transformation in women of perimenopause age taking statistical analysis into account. The results enabled us to find statistically significant risk factors for endometrial cancer. The degree of cancer risk was calculated using the method of binary logistic regression; the effective tactics of management of patients with endometrial hyperplastic processes in perimenopause was chosen.

About the authors

E. A. Kogan

Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation

Email: vnamiot@gmail.com
Russian Federation, Moscow, 119991

A. L. Unanyan

Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation

Email: vnamiot@gmail.com
Russian Federation, Moscow, 119991

V. A. Namiot

Institute of Nuclear Physics, Moscow State University

Author for correspondence.
Email: vnamiot@gmail.com
Russian Federation, Moscow, 119991

D. V. Baburin

Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation

Email: vnamiot@gmail.com
Russian Federation, Moscow, 119991

S. N. Udaltsov

Institute of Physicochemical and Biological Problems in Soil Science, Russian Academy of Sciences

Email: vnamiot@gmail.com
Russian Federation, Pushchino, Moscow oblast, 142290

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