The Effect of Mobile Phone Radiation on in vitro Platelet Aggregation in Patients with Polycythemia Vera and Ischemic Stroke


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Abstract

Abstract—The influence of exposure to mobile phone radiation on in vitro platelet aggregation has been studied. It has been shown that a 30-min exposure of blood samples to mobile phone radio frequency waves increases ADP-induced platelet aggregation in groups of healthy volunteers and patients with stroke, whereas platelet aggregation in JAKV617F-positive patients with polycythemia vera is significantly suppressed and is eventually completely inhibited. The mechanisms that underlie this phenomenon may be associated with cell oxidative stress and anomalies the JAK2 signal transduction pathway in malignized blood cells. The results indicate that it is important to set safety standards for the use of mobile devices by patients with various diseases.

About the authors

I. A. Olkhovskiy

Aff1; Aff2

Author for correspondence.
Email: krashemcenter@mail.ru
Russian Federation, Federal Research Center “Krasnoyarsk Scientific Center of the Siberian Branch of the Russian Academy of Sciences”, Krasnoyarsk, 660036; Krasnoyarsk Branch of the “National Research Center for Hematology”, Krasnoyarsk, 660036

M. A. Stolyar

Aff2; Siberian Federal University

Email: krashemcenter@mail.ru
Russian Federation, Krasnoyarsk Branch of the “National Research Center for Hematology”, Krasnoyarsk, 660036; Krasnoyarsk, 660041

D. V. Lagutinskaya

Siberian Federal University

Email: krashemcenter@mail.ru
Russian Federation, Krasnoyarsk, 660041

V. E. Zakhvataev

Aff1; Siberian Federal University

Email: krashemcenter@mail.ru
Russian Federation, Federal Research Center “Krasnoyarsk Scientific Center of the Siberian Branch of the Russian Academy of Sciences”, Krasnoyarsk, 660036; Krasnoyarsk, 660041

R. G. Khlebopros

Aff1; Siberian Federal University

Email: krashemcenter@mail.ru
Russian Federation, Federal Research Center “Krasnoyarsk Scientific Center of the Siberian Branch of the Russian Academy of Sciences”, Krasnoyarsk, 660036; Krasnoyarsk, 660041

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