The remote effects of radiation after hypofractionated irradiation with protons of Ehrlich ascites carcinoma in mice


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This work focuses on the study of remote effects (duration of remission, recurrence rate, and average lifespan) in mice with Ehrlich ascites carcinoma exposed to oligofractionated irradiation with a pencil scanning beam of protons depending on the volume of the tissue being irradiated and the interval between dose fractions. The results show higher antitumor efficacy and a considerable increase in the average life span of mice after hypofractionated irradiation with a pencil scanning beam of protons at a total dose of 60 Gy of the gross tumor volume compared with the planning target volume.

作者简介

V. Balakin

Physical Technical Center, Lebedev Physical Institute

Email: szaichkina@yandex.ru
俄罗斯联邦, Protvino, Moscow Region, 142280

A. Shemyakov

Physical Technical Center, Lebedev Physical Institute

Email: szaichkina@yandex.ru
俄罗斯联邦, Protvino, Moscow Region, 142280

S. Zaichkina

Institute of Theoretical and Experimental Biophysics

编辑信件的主要联系方式.
Email: szaichkina@yandex.ru
俄罗斯联邦, Pushchino, Moscow Region, 142290

O. Rozanova

Institute of Theoretical and Experimental Biophysics

Email: szaichkina@yandex.ru
俄罗斯联邦, Pushchino, Moscow Region, 142290

E. Smirnova

Institute of Theoretical and Experimental Biophysics

Email: szaichkina@yandex.ru
俄罗斯联邦, Pushchino, Moscow Region, 142290

S. Romanchenko

Institute of Theoretical and Experimental Biophysics

Email: szaichkina@yandex.ru
俄罗斯联邦, Pushchino, Moscow Region, 142290

S. Sorokina

Institute of Theoretical and Experimental Biophysics

Email: szaichkina@yandex.ru
俄罗斯联邦, Pushchino, Moscow Region, 142290

N. Strelnikova

Physical Technical Center, Lebedev Physical Institute

Email: szaichkina@yandex.ru
俄罗斯联邦, Protvino, Moscow Region, 142280

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