The modeling of rat EEG signals in absence epilepsy in the analysis of brain connectivity


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Abstract

Simple models that describe some features of the electrical brain activity in rats with genetic absence epilepsy recorded before and after an epileptic seizure have been proposed in this study. These models can help to analyze the efficiency of the Granger causality analysis of the directional connectivity determination. The comparison of the results of the experimental and modeled signal analysis, on one hand, reveals a number of artifacts of this method, and on the other hand, proves its effectiveness in the research on absence epilepsy mechanisms.

About the authors

M. V. Sysoeva

Gagarin Saratov State Technical University

Author for correspondence.
Email: bobrichek@mail.ru
Russian Federation, ul. Politekhnicheskaya 77, Saratov, 410054

G. D. Kuznetsova

Institute of Higher Nervous Activity and Neurophysiology

Email: bobrichek@mail.ru
Russian Federation, ul. Butlerova 5a, Moscow, 117485

I. V. Sysoev

Chernyshevsky Saratov State University

Email: bobrichek@mail.ru
Russian Federation, ul. Astrakhanskaya 83, Saratov, 410012

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