Chemiresistive Sensors for Thrombin Assay Based on Nanosize Carbon Nanotube Films on Flexible Supports
- Авторы: Komarov I.A.1, Rubtsova E.N.1, Lapashina A.S.2, Golovin A.V.2, Bobrinetskiy I.I.1
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Учреждения:
- National Research University of Electronic Technology (MIET)
- Faculty of Bioengineering and Bioinformatics, M. V. Lomonosov Moscow State University
- Выпуск: Том 51, № 6 (2018)
- Страницы: 377-380
- Раздел: Theory and Design
- URL: https://journals.rcsi.science/0006-3398/article/view/235320
- DOI: https://doi.org/10.1007/s10527-018-9753-8
- ID: 235320
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Аннотация
We present here results obtained during the developmental construction of a selective biological sensor based on carbon nanotubes chemically modified with specific aptamers. The sensory layer, consisting of a film of carbon nanotubes, on a flexible polymer substrate, provides high sensitivity for assay of the target proteins. The responses of the sensory structures to the target protein − thrombin and a reference protein, albumin − were studied. Selective estimation of thrombin after exposure of the sensor to albumin was demonstrated.
Об авторах
I. Komarov
National Research University of Electronic Technology (MIET)
Автор, ответственный за переписку.
Email: master_kom@mail.ru
Россия, Moscow, Zelenograd
E. Rubtsova
National Research University of Electronic Technology (MIET)
Email: master_kom@mail.ru
Россия, Moscow, Zelenograd
A. Lapashina
Faculty of Bioengineering and Bioinformatics, M. V. Lomonosov Moscow State University
Email: master_kom@mail.ru
Россия, Moscow
A. Golovin
Faculty of Bioengineering and Bioinformatics, M. V. Lomonosov Moscow State University
Email: master_kom@mail.ru
Россия, Moscow
I. Bobrinetskiy
National Research University of Electronic Technology (MIET)
Email: master_kom@mail.ru
Россия, Moscow, Zelenograd
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