Chemiresistive Sensors for Thrombin Assay Based on Nanosize Carbon Nanotube Films on Flexible Supports


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We present here results obtained during the developmental construction of a selective biological sensor based on carbon nanotubes chemically modified with specific aptamers. The sensory layer, consisting of a film of carbon nanotubes, on a flexible polymer substrate, provides high sensitivity for assay of the target proteins. The responses of the sensory structures to the target protein − thrombin and a reference protein, albumin − were studied. Selective estimation of thrombin after exposure of the sensor to albumin was demonstrated.

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I. Komarov

National Research University of Electronic Technology (MIET)

编辑信件的主要联系方式.
Email: master_kom@mail.ru
俄罗斯联邦, Moscow, Zelenograd

E. Rubtsova

National Research University of Electronic Technology (MIET)

Email: master_kom@mail.ru
俄罗斯联邦, Moscow, Zelenograd

A. Lapashina

Faculty of Bioengineering and Bioinformatics, M. V. Lomonosov Moscow State University

Email: master_kom@mail.ru
俄罗斯联邦, Moscow

A. Golovin

Faculty of Bioengineering and Bioinformatics, M. V. Lomonosov Moscow State University

Email: master_kom@mail.ru
俄罗斯联邦, Moscow

I. Bobrinetskiy

National Research University of Electronic Technology (MIET)

Email: master_kom@mail.ru
俄罗斯联邦, Moscow, Zelenograd

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