Мақаланы E-mail арқылы жіберу Study of heme and globin conformation in fractionated rat erythrocytes by means of raman spectroscopy
- Авторлар: Yushkov B.1,2, Zuev M.3, Brilliant S.1,2, Vasin A.3
-
Мекемелер:
- Institute of Immunology and Physiology, Ural Branch of the Russian Academy of Sciences
- GAUZ SO “Institute for Medical Cell Technologies”
- Institute of Solid State Chemistry, Ural Branch of the Russian Academy of Sciences
- Шығарылым: Том 68, № 1 (2023)
- Беттер: 33-40
- Бөлім: Articles
- URL: https://journals.rcsi.science/0006-3029/article/view/144402
- DOI: https://doi.org/10.31857/S0006302923010040
- EDN: https://elibrary.ru/NZMURQ
- ID: 144402
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
Conformational changes of heme and globin in fractionated rat erythrocytes have been investigated using Raman spectroscopy. The results obtained show that normal isoforms (common variants) of hemoglobin, which plays a key role in oxygen transport and a protective role against oxidative stress, are dominant (more than 80%) in rat blood. However, heavy chain (3%) and light chain isoforms (11%) formed as a result of protein polymerization or degradation perform important roles in the body because they also function in signal transmission and binding to exogenous ligands.
Негізгі сөздер
Авторлар туралы
B. Yushkov
Institute of Immunology and Physiology, Ural Branch of the Russian Academy of Sciences;GAUZ SO “Institute for Medical Cell Technologies”Yekaterinburg, Russia
M. Zuev
Institute of Solid State Chemistry, Ural Branch of the Russian Academy of SciencesYekaterinburg, Russia
S. Brilliant
Institute of Immunology and Physiology, Ural Branch of the Russian Academy of Sciences;GAUZ SO “Institute for Medical Cell Technologies”
Email: svetlana.brilliant@bk.ru
Yekaterinburg, Russia
A. Vasin
Institute of Solid State Chemistry, Ural Branch of the Russian Academy of SciencesYekaterinburg, Russia
Әдебиет тізімі
- А. Н. Федяшкина и Г. В. Максимов, Вестн. Мордов. универ., 3 (4), 141 (2013).
- A. Bogdanova, L. Kaesthner, et al., Rev. Artic. Front. Physiol., 11, 392 (2020).
- И. К. Проскурина и А. В. Титовский, Яросл. педагогич. вестн., 3 (21), 83 (1999).
- M. Z. Lu, Y. J. Guo, et al., Spectroscopy and Spectral Analysis, 34 (2), 439 (2014).
- Б. Г. Юшков и С. А. Бриллиант, Рос. физиол. журн. им. И. М. Сеченова, 106 (10), 1312 (2020)
- Б. Г. Юшков и С. А. Бриллиант, Бюл. эксперим. биологии и медицины, 173 (1), 16 (2022).
- П. Кэри, Применения спектроскопии КР и РКР в биохимии ("Мир", М., 1985).
- О. В. Слатинская, О. Г. Лунева и др. Биофизика, 65 (2), 250 (2020).
- О. В. Слатинская и Г. В. Максимов, Актуал. вопр. биологии, физики и химии, 4 (2), 283 (2019).
- И. А. Хуторская, В. П. Балашов и др. Вестн. нов. мед. техн., 23 (3), 55 (2016).
- K. Ramser, K. Logg, et al. J. Biomed. Opt., 9, 593 (2004).
- N. A. Brazhe, S. Abdali, A. R. Brazhe, et al., Biophys. J., 97 (12), 3206 (2009).
- V. V. Revin, N. V. Gromova, et al., BioMed Res.Int., 973 (2015).
- I. V. Syusin, V. V. Revin, et al., Biol. Med., 7, 239 (2015).
- H. Holtje, W. Sippl, et al., Molecular Modeling. Third edition (Wiley-VCH Verlag, Weinheim, 2008).
- А. И. Юсипович, Н. А. Браже и др., Бюл. эксперим. биологии и медицины, 155 (2), 201 (2013)
- И. В. Сюсин, Дисс.... канд. биол. наук (Мордов. гос. ун-т им. Н.П. Огарева, Воронеж, 2015).
- С. С. Бочкарева, Дисс.... канд. биол. наук (МГУ имени М.В. Ломоносова, М., 2016).
- Э. И. Никельшпарг, Дисс.... канд. биол. наук (МГУ имени М.В. Ломоносова, М., 2019).
- C. R. Haney and P. W. Buehler, Adv. Drug. Deliv., 40 (3), 153 (2000)
- V. Budhiraja and J. D. Hellums, Microvasc. Res., 64 (2), 220 (2002).
