Nucleolar methyltransferase fibrillarin: Evolution of structure and functions
- Авторлар: Shubina M.1, Musinova Y.1, Sheval E.1
-
Мекемелер:
- Lomonosov Moscow State University
- Шығарылым: Том 81, № 9 (2016)
- Беттер: 941-950
- Бөлім: Review
- URL: https://journals.rcsi.science/0006-2979/article/view/150997
- DOI: https://doi.org/10.1134/S0006297916090030
- ID: 150997
Дәйексөз келтіру
Аннотация
Fibrillarin is one of the most studied nucleolar proteins. Its main functions are methylation and processing of pre-rRNA. Fibrillarin is a highly conserved protein; however, in the course of evolution from archaea to eukaryotes, it acquired an additional N-terminal glycine and arginine-rich (GAR) domain. In this review, we discuss the evolution of fibrillarin structure and its relation to the functions of the protein in prokaryotes and eukaryotes.
Негізгі сөздер
Авторлар туралы
M. Shubina
Lomonosov Moscow State University
Email: evsheval@gmail.com
Ресей, Moscow, 119991
Y. Musinova
Lomonosov Moscow State University
Email: evsheval@gmail.com
Ресей, Moscow, 119991
E. Sheval
Lomonosov Moscow State University
Хат алмасуға жауапты Автор.
Email: evsheval@gmail.com
Ресей, Moscow, 119991