Nucleolar methyltransferase fibrillarin: Evolution of structure and functions
- Авторы: Shubina M.1, Musinova Y.1, Sheval E.1
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Учреждения:
- Lomonosov Moscow State University
- Выпуск: Том 81, № 9 (2016)
- Страницы: 941-950
- Раздел: Review
- URL: https://journals.rcsi.science/0006-2979/article/view/150997
- DOI: https://doi.org/10.1134/S0006297916090030
- ID: 150997
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Аннотация
Fibrillarin is one of the most studied nucleolar proteins. Its main functions are methylation and processing of pre-rRNA. Fibrillarin is a highly conserved protein; however, in the course of evolution from archaea to eukaryotes, it acquired an additional N-terminal glycine and arginine-rich (GAR) domain. In this review, we discuss the evolution of fibrillarin structure and its relation to the functions of the protein in prokaryotes and eukaryotes.
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Об авторах
M. Shubina
Lomonosov Moscow State University
Email: evsheval@gmail.com
Россия, Moscow, 119991
Y. Musinova
Lomonosov Moscow State University
Email: evsheval@gmail.com
Россия, Moscow, 119991
E. Sheval
Lomonosov Moscow State University
Автор, ответственный за переписку.
Email: evsheval@gmail.com
Россия, Moscow, 119991
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