Gender peculiarities of critical lower limb ischemia

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Abstract

BACKGROUND: Development of critical ischemia of lower limbs in patients with atherosclerosis causes negative consequences due to the high probability of detecting multilevel changes, as well as identifying coronary and carotid pools.

АIM: The aim of the study was to investigate gender differences in critical lower limb ischemia of atherosclerotic genesis following reconstructive interventions.

MATERIALS AND METHODS: Arterial reconstructions have been performed in 261 patients with peripheral atherosclerosis (95 women and 166 men). The specific features of reconstructive interventions have been taken into account; complications and the number of amputations have been analyzed in the early period.

RESULTS: Higher pulse pressure has been registered in the female group; tibial arteries have been affected significantly more frequently (p < 0,05). Thrombosis of the operated segment has been observed more frequently in the male patients at the stage of critical ischemia; in the case of claudication the complications were sporadic.

CONCLUSIONS: The best results of reconstructive care in men and women with peripheral atherosclerosis at the claudication stage determine the vector of active tactics in the absence of conservative treatment results.

About the authors

Nikolay I. Glushkov

North-Western State Medical University named after I.I. Mechnikov

Email: nikolay.glushkov@szgmu.ru
ORCID iD: 0000-0001-8146-4728

MD, Dr. Sci. (Med.), Professor

Russian Federation, 47 Piskarevsky Ave., Saint Petersburg, 195067

Petr D. Puzdriak

North-Western State Medical University named after I.I. Mechnikov

Email: hirurg495@yandex.ru
ORCID iD: 0000-0003-2631-3622
Scopus Author ID: 57194489779
ResearcherId: K-9787-2016

MD
Russian Federation, 47 Piskarevsky Ave., Saint Petersburg, 195067

Anastasia N. Agurbash

North-Western State Medical University named after I.I. Mechnikov

Email: nastaagurbash@mail.ru
ORCID iD: 0000-0003-1247-3481
Russian Federation, 47 Piskarevsky Ave., Saint Petersburg, 195067

Anatoly V. Razepin

North-Western State Medical University named after I.I. Mechnikov

Email: razepint@rambler.ru
ORCID iD: 0000-0003-0470-4681
Russian Federation, 47 Piskarevsky Ave., Saint Petersburg, 195067

Mikhail A. Ivanov

North-Western State Medical University named after I.I. Mechnikov

Author for correspondence.
Email: iv30407302007@yandex.ru
ORCID iD: 0000-0002-4756-6488

MD, Dr. Sci. (Med.), Professor

Russian Federation, 47 Piskarevsky Ave., Saint Petersburg, 195067

References

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Supplementary files

Supplementary Files
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1. JATS XML
2. Fig. 1. Differences in the incidence of tibial segment involvement and needs for endovascular care in the study groups

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3. Fig. 2. The value of perioperative blood loss in the analysis groups

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4. Fig. 3. The frequency of thrombosis of the operated segment in the analyzed groups against the background of critical ischemia of the lower extremities and claudication. CLI — critical lower limb ischemia

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Copyright (c) 2021 Glushkov N.I., Puzdriak P.D., Agurbash A.N., Razepin A.V., Ivanov M.A.

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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