ULTRASOUND INVESTIGATION POSSIBILITIES IN PARATHYROID GLANDSESTIMATION IN SECONDARY HYPERPARATHYROIDISM

It was assessed the efficacy of the parathyroid gland (PTG) ultrasonography in secondary hyperparathyroidism (SHRT). The data of 120 patients with the diagnosis of SHPT were analyzed. The majority of patients (44,2%) had chronic glomerulonephritis, 59,2% of patients were on hemodialysis,40,8% - on peritoneal dialysis. In 62,3% of cases, an increase in the size of the glands was found, combined with a change in the echostructure. The amount of PTG in one patient was from 1 to 5, ectopic glands were found in 5,4% of cases. In the majority of patients with hyperplastic PTG (68,3%) the increase in the level of parathyroid hormone was more than 300 pg / ml.diffuse hyperplasia was detected in 37,7% of cases, nodal hyperplasia - in 62,3% of cases. The characteristics of ultrasonography with regard to the detection of nodular hyperplasia in case of inhomogeneity of PTG echostructure are: accuracy - 85,7%; sensitivity - 82,4%, specificity - 86,9%, in terms of determining the size of the PTG, the characteristics of the method are: accuracy - 75,8%; sensitivity- 79,3%; specificity - 68,2%.The conclusion is made that ultrasonography is a highly informative method for diagnosing hyperplasia of the prostate gland in patients with SHPT, which allows timely detection of changes in the glands, determining the severity of hyperplasia, suggesting a morphological variant of the observed changes, and increasing the effectiveness of the operative intervention in the PTG.

parathyroid glands, thyroid gland, secondary hyperparathyroidism, ultrasound, chronic kidney disease, parathyroid hormone, sensitivity, specificity