Evaluation of the quality of life dynamics in comorbid patients with hip and knee joint arthroplasty
- Authors: Aliev B.G.1, Spichko A.A.2, Saiganov S.A.1, Mazurov V.I.1, Korneenkov A.A.3, Mansurov D.S.4, Khaydarov V.M.1, Urazovskaya I.L.1, Tkachenko A.N.1
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Affiliations:
- North-Western State Medical University named after I.I. Mechnikov
- V.A. Baranov Republican Hospital
- Kirov Military Medical Academy
- Samarkand State Medical University
- Issue: Vol 15, No 1 (2023)
- Pages: 33-42
- Section: Original research
- URL: https://journals.rcsi.science/vszgmu/article/view/131092
- DOI: https://doi.org/10.17816/mechnikov112015
- ID: 131092
Cite item
Abstract
BACKGROUND: In recent years, in traumatology and orthopedics, statistical methods of survival analysis have been used to assess long-term treatment results, which make it possible to take into account censored clinical observations. This method of statistical analysis allows to take into account both cases of attrition from care and cases of incomplete follow-ups. There is no concurrent point of view on the dependence of the long-term results of hip and knee arthroplasty on the comorbidity of a patient. This circumstance fosters a special study using survival analysis.
AIM: To study the long-term results of total hip and knee arthroplasty in the patients with osteoarthritis. To determine the patients’ quality of life depending on the presence of pronounced concomitant pathology.
MATERIALS AND METHODS: The groups of patients with comorbidity and without significant concomitant pathology have been compared. The first group included 806 patients aged 19 to 88 years who underwent primary total hip replacement in the Clinic of Traumatology and Orthopedics of the North-Western State Medical University named after I.I. Mechnikov from 2014 to 2018 in connection with osteoarthritis. The second group consisted of 376 patients aged 43 to 85 years who underwent primary total KR due to osteoarthritis in the V.A. Baranov Republican Hospital (Petrozavodsk) in 2016–2019. Statistical data processing and graph design have been carried out with R programming language with open access via https://cran.r-project.org. The probability of maintaining a satisfactory assessment of the quality of life by a certain observation point t (year of observation) has been assessed using the Kaplan–Mayer method. The logrank test has been used in order to compare the probability of maintaining a satisfactory assessment of quality of life during the entire follow-up period in the groups of patients with and without polymorbidity.
RESULTS: At the end of the 5th year of follow-up, the probability of maintaining excellent and good quality of life after hip replacement with a 95% confidence interval was 0.88 (0.81; 0.94) in the patients without comorbidity, 0.84 (0.79; 0.88) in the patients with severe concomitant pathology. Test statistics (Z = 0.93) and p = 0.31 indicate statistically insignificant differences in survival curves between the groups of patients with varying degrees of comorbidity.
When analyzing the five-year results of the knee replacement, the quality of life among patients with high and low comorbidity did not differ significantly. The probability of excellent and good quality of life at the 5th year of follow-up in practically healthy patients and in cases of mild therapeutic disease was 0.78 (0.67; 0.88); with a high degree of comorbidity — 0.74 (0.65; 0.81).
CONCLUSIONS: By the end of the 5th year of follow-up of the patients who have undergone hip or knee replacement due to osteoarthritis, an excellent and good quality of life can be expected on average in 80% of the patients. Satisfactory and unsatisfactory — in 20% of the patients. Excellent and good quality of life 5 years after hip or knee arthroplasty in the patients with severe comorbidity does not significantly differ from that in the practically healthy patients without comorbidity (p > 0,05).
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##article.viewOnOriginalSite##About the authors
Bahtiyar G. Aliev
North-Western State Medical University named after I.I. Mechnikov
Email: dr.aliyev@mail.ru
ORCID iD: 0000-0003-0664-6198
SPIN-code: 2418-2040
Russian Federation, 41 Kirochnaya St., Saint Petersburg, 191015
Aleksandr A. Spichko
V.A. Baranov Republican Hospital
Email: dr.nl@mail.ru
ORCID iD: 0000-0002-9355-1068
SPIN-code: 3476-8212
Russian Federation, Petrozavodsk
Sergey A. Saiganov
North-Western State Medical University named after I.I. Mechnikov
Email: sergey.sayganov@szgmu.ru
ORCID iD: 0000-0001-8325-1937
SPIN-code: 2174-6400
MD, Dr. Sci. (Med.), Professor
Russian Federation, 41 Kirochnaya St., Saint Petersburg, 191015Vadim I. Mazurov
North-Western State Medical University named after I.I. Mechnikov
Email: rectorat@szgmu.ru
ORCID iD: 0000-0002-0797-2051
SPIN-code: 6823-5482
Scopus Author ID: 16936315400
ResearcherId: J-9643-2014
MD, Dr. Sci. (Med.), Professor, Аcademician of the Russian Academy of Sciences
Russian Federation, 41 Kirochnaya St., Saint Petersburg, 191015Aleksey A. Korneenkov
Kirov Military Medical Academy
Email: korneyenkov@gmail.com
ORCID iD: 0000-0001-5870-8042
SPIN-code: 2396-1530
Scopus Author ID: 55867251500
ResearcherId: B-9033-2016
MD, Dr. Sci. (Med.), Professor
Russian Federation, 41 Kirochnaya St., Saint Petersburg, 191015Djalolidin S. Mansurov
Samarkand State Medical University
Email: jalolmedic511@gmail.com
ORCID iD: 0000-0002-1799-641X
SPIN-code: 1330-6583
Scopus Author ID: 57194974175
MD, Cand. Sci. (Med.)
Uzbekistan, SamarkandValerii M. Khaydarov
North-Western State Medical University named after I.I. Mechnikov
Email: drxaydarov@mail.ru
ORCID iD: 0000-0002-0754-4348
SPIN-code: 7083-3254
MD, Cand. Sci. (Med.)
Russian Federation, 41 Kirochnaya St., Saint Petersburg, 191015Irina L. Urazovskaya
North-Western State Medical University named after I.I. Mechnikov
Email: langelova@yandex.ru
ORCID iD: 0000-0003-4165-4599
SPIN-code: 9263-4316
Scopus Author ID: 36544644000
MD, Cand. Sci. (Med.)
Russian Federation, 41 Kirochnaya St., Saint Petersburg, 191015Aleksandr N. Tkachenko
North-Western State Medical University named after I.I. Mechnikov
Author for correspondence.
Email: altkachenko@mail.ru
ORCID iD: 0000-0003-4585-5160
SPIN-code: 2658-0405
Scopus Author ID: 57194971668
ResearcherId: O-3606-2014
MD, Dr. Sci. (Med.), Professor
Russian Federation, 41 Kirochnaya St., Saint Petersburg, 191015References
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