Persistent dysuria in women: etiological diagnostics and treatment
- Authors: Slesarevskaya M.N.1, Ignashov Y.A.1, Kuzmin I.V.1, Al-Shukri S.K.1
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Affiliations:
- Academician I.P. Pavlov First St. Petersburg State Medical University
- Issue: Vol 11, No 3 (2021)
- Pages: 195-204
- Section: Original articles
- URL: https://journals.rcsi.science/uroved/article/view/81948
- DOI: https://doi.org/10.17816/uroved81948
- ID: 81948
Cite item
Abstract
INTRODUCTION: Dysuria is a painful urination combined with its frequency and/or difficulty. Dysuria is observed in many urological diseases and is one of the most common reasons for treatment for urological cause.
AIM: The aim of the study is to identify the etiological factors of dysuria in women and to evaluate a personalized approach to their treatment.
MATERIALS AND METHODS: We analyzed the data of 368 women with chronical cystitis. The inclusion criteria for the study were the presence of dysuria (painful and frequent urination more than 8 times a day with or without difficulty), the prescription of urination disorders over one year old and age 18 and over. All patients underwent a comprehensive urological examination to identify the causes of urinary disorders.
RESULTS: The Bacterial cystitis was confirmed only in 78 (21.2%) patients among all 368 women. In the remaining 290 (78.8%) patients, the causes of persistent dysuria were other diseases: bladder leukoplakia in 154 (41.8%), bladder pain syndrome/interstitial cystitis in 38 (10.3%), viral cystitis in 34 (9.3%), paraurethral formations in 29 (7.9%), neurogenic urinary dysfunction bladder in 25 (6.8%), urethral pain syndrome in 5 (1.4%) patients. Dysuria was also caused by postradiation cystitis (2 patients), secondary stones in the urinary bladder (2 patients), and one patient had extragenital endometriosis.
CONCLUSIONS: The variety of reasons for the development of persistent dysuria in women requires careful examination of patients. Treatment should be carried out only after accurate verification of the diagnosis.
Full Text
##article.viewOnOriginalSite##About the authors
Margarita N. Slesarevskaya
Academician I.P. Pavlov First St. Petersburg State Medical University
Email: mns-1971@yandex.ru
ORCID iD: 0000-0002-4911-6018
SPIN-code: 9602-7775
Scopus Author ID: 57196117211
Cand. Sci. (Med.)
Russian Federation, 6–8, Lva Tolstogo str., Saint Petersburg, 197022Yuriy A. Ignashov
Academician I.P. Pavlov First St. Petersburg State Medical University
Author for correspondence.
Email: yuri.ignashov@gmail.com
ORCID iD: 0000-0003-0773-0711
SPIN-code: 2243-0734
Cand. Sci. (Med.)
Russian Federation, 6–8, Lva Tolstogo str., Saint Petersburg, 197022Igor V. Kuzmin
Academician I.P. Pavlov First St. Petersburg State Medical University
Email: kuzminigor@mail.ru
ORCID iD: 0000-0002-7724-7832
SPIN-code: 2684-4070
Scopus Author ID: 56878681300
Dr. Sci. (Med.), Professor
Russian Federation, 6–8, Lva Tolstogo str., Saint Petersburg, 197022Salman Kh. Al-Shukri
Academician I.P. Pavlov First St. Petersburg State Medical University
Email: alshukri@mail.ru
ORCID iD: 0000-0002-4857-0542
SPIN-code: 2041-8837
Scopus Author ID: 6506423220
Dr. Sci. (Med.), Professor, Head of the Department of Urology
Russian Federation, 6–8, Lva Tolstogo str., Saint Petersburg, 197022References
- Bremnor JD, Sadovsky R. Evaluation of dysuria in adults. Am Fam Physician. 2002;65(8):1589–1596.
- Michels TC, Sands JE. Dysuria: Evaluation and Differential Diagnosis in Adults. Am Fam Physician. 2015;92(9):778–786.
- Kogan MI, Kalinichenko SYu, Avadiyeva NE. Sexual dysfunction in women with symptoms of irritation of lower urinary tract: new field of urogynecological researches. Problems of Women Health. 2008;3(4):14–17. (In Russ.)
- Slesarevskaya MN, Kuzmin IV, Ignashov YuA. Characteristics of symptoms and psychosomatic status in women with chronic pelvic pain syndrome. Urologicheskie vedomosti. 2015;5(3):16–19. (In Russ.) doi: 10.17816/uroved5316-19
- Mehta P, Leslie SW, Reddivari AKR. Dysuria. 2021 Aug 12. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan. Available from: https://www.ncbi.nlm.nih.gov/books/NBK549918/
- Neymark AI, Chulyukova II, Mazyrko AV. Treatment of stable dysuria in women. Urology. 2003;(1):46–49. (In Russ.)
- Loran OB, Sinjakova LA. Lejkoplakija mochevogo puzyrja kak prichina stojkoj dizurii. Medical council. 2009;(1):9–12. (In Russ.)
- Neymark AI, Neymark BA, Kondrat’eva JuS. Dizuricheskij sindrom u zhenshhin. Moscow: GЕOTAR-Media; 2010. 256 p.
- Loran OB, Sinyakova LA, Vinarova NA, Nikiforov NV. Persistent dysuria in women. Current issues in diagnosis and treatment. Urology. 2013;(2):5–8. (In Russ.)
- Kuzmin IV. Epidemiological aspects of overactive bladder and urge urinary incontinence. Urologicheskie vedomosti. 2015;5(3): 30–34. (In Russ.) doi: 10.17816/uroved5330-34
- Shishkov VV, Kokurenkova PA, Il’ichjov A. Psychogenic Dysuriab. Pediatrician. 2020;11(5):73–79. (In Russ.)
- Birder LA. More than just a barrier: urothelium as a drug target for urinary bladder pain. Am J Physiol Renal Physiol. 2005;289(3): F489–F495. doi: 10.1152/ajprenal.00467.2004
- Michel MC, Chapple CR. Basic mechanisms of urgency: preclinical and clinical evidence. Eur Urol. 2009;56(2):298–307. doi: 10.1016/j.eururo.2009.05.028
- Viltsanyuk IA, Chernukha SN. Features of the differential diagnosis and treatment of a dysuria syndrome at pre- and post-menopausal age women. Crimean Journal of Internal Diseases. 2013;2(21):93–98. (In Russ.)
- Palagin IS, Sukhorukova MV, Dekhnich AV, et al. Current state of antibiotic resistance of pathogens causing community-acquired urinary tract infections in Russia, Belarus and Kazakhstan: results of the international multicenter study “Darmis-2018”. Urology. 2020;(1):19–31. (In Russ.) doi: 10.18565/urology.2020.1.19-31
- Al-Shukri SH, Slesarevskaya MN, Kuzmin IV. Use of fosfomycin in uncomplicated urinary tract infections. Urology. 2018;(5):153–159. (In Russ.) doi: 10.18565/urology.2018.5.153-158
- Kuzmin IV, Al-Shukri SH, Slesarevskaya MN. Treatment and prophylaxis of the lower urinary tract recurrent infections in women. Urologicheskie vedomosti. 2019;9(2):5–10. (In Russ.) doi: 10.17816/uroved925-10
- Al-Shukri SH, Kuzmin IV, Slesarevskaya MN, et al. Disorders of urination in patients with chronic pelvic pain syndrome and bladder leukoplakia. Urologicheskie vedomosti. 2016;6(2):5–10. (In Russ.) doi: 10.17816/uroved625-10
- Slesarevskaya MN, Al-Shukri SKh, Sokolov AV, Kuzmin IV. Clinical course and surgical treatment of paraurethral cysts in women. Urologicheskie vedomosti. 2019;9(4):5–10. (In Russ.) doi: 10.17816/uroved945-10
- Kaprin AD, Kostin AA, Semin AV, Nesterov PV. Experience of use of drug ingaron (recombinant human interferon gamma) in the treatment of radiation cystitis accompanied by hematuria. Farmateka. 2013;12(256):37–40. (In Russ.)
- Levin I, Groutz A, Gold R, et al. Surgical complications and medium-term outcome results of tension-free vaginal tape: a prospective study of 313 consecutive patients. Neurourol Urodyn. 2004;23(1):7–9. doi: 10.1002/nau.10164
- Maccagnano C, Pellucchi F, Rocchini L, et al. Diagnosis and treatment of bladder endometriosis: state of the art. Urol Int. 2012;89(3):249–58. doi: 10.1159/000339519
- Borisov VV. Diagnosis and therapy of urinary infections. What should always remember (clinical lecture). Part 1. Urologicheskie vedomosti. 2017;7(3):52–59. (In Russ.) doi: 10.17816/uroved7352-59
- Sumati AH, Saritha NK. Association of urinary tract infection in women with bacterial vaginosis. J Global Infect Dis. 2009;1(2): 151–152. doi: 10.4103/0974-777X.56254
- Gilbert NM, O’Brien VP, Lewis AL. Transient microbiota exposures activate dormant Еscherichia coli infection in the bladder and drive severe outcomes of recurrent disease. PloS Pathog. 2017;13(3): e1006238. doi: 10.1371/journal.ppat.1006238
- Neymark AI, Shelkovnikova NV. Endovascular treatment of persistent dysuria and chronic pelvic pain in women with pelvic varicose veins. Urology. 2012;(4):20–24. (In Russ.)
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