Аnaphylactic shock. Сlinical guidelines

  • Authors: Astafieva N.G.1, Bayalieva A.Z.2,3, Zabolotskikh I.B.3,4, Ilyina N.I.5,6, Kulikov A.V.3,7, Latysheva T.V.6,8, Lebedinskii K.М.3,9, Musaeva T.S.3,4, Myasnikova T.N.6, Pampura A.N.10, Fassakhov R.S.11, Khludova L.G.6, Shifman E.M.12,13
  • Affiliations:
    1. Ministry of Health and Social Development of the Russian Federation State Educational Institution of Higher Professional Education Saratov State Medical University named after V.I. Razumovsky
    2. Kazan State Medical University
    3. Russian Federation of Anesthesiologists and Reanimatologists
    4. State Budgetary educational institution of higher professional education Kuban State Medical University of the Ministry of Healthcare of the Russian Federation
    5. Russian Assotiation of Allergology and Clinical Immunology
    6. National Research Center – Institute of Immunology Federal Medical-Biological Agency of Russia
    7. Ural State Medical University
    8. Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
    9. North-Western State Medical University named after I.I. Mechnikov
    10. The Russian National Research Medical University named after N.I. Pirogov
    11. Kazan Federal University
    12. Russian Federation of Anesthesiologists and Reanimatologists,
    13. Moscow Regional Research and Clinical Institute
  • Issue: Vol 18, No 1 (2021)
  • Pages: 56-72
  • Section: Reviews
  • URL: https://journals.rcsi.science/raj/article/view/121626
  • DOI: https://doi.org/10.36691/RJA1422
  • ID: 121626

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Abstract

Anaphylactic shock is a severe life-threatening condition caused by medicines, food, hymenoptera, animal poisons, etc. Therefore, anaphylactic shock (anaphylaxis) can develop both in medical institution and outside it, and physicians of any specialties should be ready to treat this condition. In this regard, clinical guidelines for anaphylactic shock have been developed. These recommendations were approved by the Russian Association of Allergy and Clinical Immunology (Protocol No. 743/12 dated December 30, 2020) and the Federation of Anesthesiologists and Resuscitators (Protocol No. 1 dated January 13, 2021), approved at a meeting of the Scientific and Practical Council of the Ministry of Health of the Russian Federation (Protocol No. 743/12 dated December 10, 2020). Guidelines covered a number of nosologies corresponding to codes of the International Statistical Classification of Diseases and Related Health Problems: T 78.0; T 78.2; T 80.5; T 88.6. The clinical guidelines systematize modern data on etiology, epidemiology, classification, clinical picture, diagnosis, treatment, and prevention of anaphylactic shock. In addition, an algorithm for managing a patient with anaphylactic shock has been developed.

Clinical guidelines for anaphylactic shock are intended for practitioners of all specialties, students, and teachers of medical universities, residents, and graduate students.

About the authors

Natalya G. Astafieva

Ministry of Health and Social Development of the Russian Federation State Educational Institution of Higher Professional Education Saratov State Medical University named after V.I. Razumovsky

Email: astang@mail.ru
ORCID iD: 0000-0002-7691-4584
SPIN-code: 9941-7013

MD, Dr. Sci. (Med.), Professor

Russian Federation, Saratov

Ainagul Zh. Bayalieva

Kazan State Medical University; Russian Federation of Anesthesiologists and Reanimatologists

Email: bayalieva1@yandex.ru
ORCID iD: 0000-0001-7577-3284
SPIN-code: 3098-0228

MD, Dr. Sci. (Med.), Professor

Russian Federation, Kazan; Moscow

Igor B. Zabolotskikh

Russian Federation of Anesthesiologists and Reanimatologists; State Budgetary educational institution of higher professional education Kuban State Medical University of the Ministry of Healthcare of the Russian Federation

Email: zib@mail.ru
ORCID iD: 0000-0002-3556-969X
SPIN-code: 5142-1661

MD, Dr. Sci. (Med.), Professor

Russian Federation, Moscow; Krasnodar

Natalya I. Ilyina

Russian Assotiation of Allergology and Clinical Immunology; National Research Center – Institute of Immunology Federal Medical-Biological Agency of Russia

Email: instimmun@yandex.ru
SPIN-code: 6715-5650

MD, Dr. Sci. (Med.), Professor

Russian Federation, Moscow; Moscow

Alexander V. Kulikov

Russian Federation of Anesthesiologists and Reanimatologists; Ural State Medical University

Email: kulikov1905@yandex.ru
ORCID iD: 0000-0002-7768-4514
SPIN-code: 7209-3863

MD, Dr. Sci. (Med.), Professor

Russian Federation, Moscow; Yekaterinburg

Tatiana V. Latysheva

National Research Center – Institute of Immunology Federal Medical-Biological Agency of Russia; Moscow State University of Medicine and Dentistry named after A.I. Evdokimov

Email: tvlat@mail.ru
ORCID iD: 0000-0003-1508-0640
SPIN-code: 8929-7644

MD, Dr. Sci. (Med.), Professor

Russian Federation, Moscow; Moscow

Konstantin М. Lebedinskii

Russian Federation of Anesthesiologists and Reanimatologists; North-Western State Medical University named after I.I. Mechnikov

Email: mail@lebedinski.com
ORCID iD: 0000-0002-5752-4812
SPIN-code: 3590-2308

MD, Dr. Sci. (Med.), Professor

Russian Federation, Moscow; St. Petersburg

Tatiana S. Musaeva

Russian Federation of Anesthesiologists and Reanimatologists; State Budgetary educational institution of higher professional education Kuban State Medical University of the Ministry of Healthcare of the Russian Federation

Email: musayeva_tanya@mail.ru
ORCID iD: 0000-0001-9285-852X
SPIN-code: 8870-0230

MD, Cand. Sci. (Med.)

Russian Federation, Moscow; Krasnodar

Tatiana N. Myasnikova

National Research Center – Institute of Immunology Federal Medical-Biological Agency of Russia

Author for correspondence.
Email: t_miasnikova@mail.ru
ORCID iD: 0000-0001-8491-195X
SPIN-code: 4684-3112

MD, Cand. Sci. (Med.)

Russian Federation, Moscow

Alexander N. Pampura

The Russian National Research Medical University named after N.I. Pirogov

Email: apampura1@mail.ru
ORCID iD: 0000-0001-5039-8473
SPIN-code: 9722-7961

MD, Dr. Sci. (Med.), Professor

Russian Federation, Moscow

Rustem S. Fassakhov

Kazan Federal University

Email: farrus@mail.ru
ORCID iD: 0000-0001-9322-2689
SPIN-code: 1748-7760

MD, Dr. Sci. (Med.), Professor

Russian Federation, Kazan

Ludmila G. Khludova

National Research Center – Institute of Immunology Federal Medical-Biological Agency of Russia

Email: Lg.khludova@gmail.com
ORCID iD: 0000-0003-3767-0924
SPIN-code: 3335-3394

MD

Russian Federation, Moscow

Efim M. Shifman

Russian Federation of Anesthesiologists and Reanimatologists,; Moscow Regional Research and Clinical Institute

Email: eshifman@mail.ru
ORCID iD: 0000-0002-6113-8498
SPIN-code: 4582-8494

MD, Dr. Sci. (Med.), Professor

Russian Federation, Moscow; Moscow

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Supplementary files

Supplementary Files
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1. JATS XML
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2. Appendix A1. Composition of the working group for the development and revision of clinical guidelines

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3. Appendix A2. Guidelines development methodology

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4. Guidelines development methodology

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5. Attachment 1. The Evidence Confidence Level (EIR) Scale for Diagnostic Methods (diagnostic interventions)

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6. Appendix 2. Scale for assessing the levels of confidence in evidence (LOI) for methods of prevention, treatment and rehabilitation (preventive, curative, rehabilitative interventions)

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7. Appendix 3. The scale for assessing the levels of persuasiveness of recommendations (SDL) for methods of prevention, diagnosis, treatment and rehabilitation (preventive, diagnostic, therapeutic, rehabilitation interventions)

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8. Procedure for updating clinical guidelines

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9. Appendix A3. References, including suitability of indications for use and contraindications, methods of administration and doses of drugs, instructions for use of the drug

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10. Appendix A4. Recommended anti-shock kit (for treatment rooms, dental offices)

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11. Appendix B. Algorithm of the doctor's actions Algorithm for managing a patient with AS

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12. Appendix B. Patient Information

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13. Appendix D. Assessment scales, questionnaires and other assessment instruments of the patient's condition, given in clinical guidelines

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