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Post a Comment Capabilities of voxel based morphometry and diffusion tensor imaging in diagnostics of bilateral spastic forms of cerebral palsy
- Authors: Lvov V.S.1, Pozdnyakov A.V.1, Ivanov D.O.1, Tashilkin A.I.1, Makarov L.M.1, Pozdnyakova O.F.1, Melashenko T.V.1, Bessonova L.B.2, Popov P.A.2, Aleksandrovich V.Y.1
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Affiliations:
- St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
- Saint Olga City Children’s Hospital
- Issue: Vol 10, No 1 (2019)
- Pages: 29-36
- Section: Articles
- URL: https://journals.rcsi.science/pediatr/article/view/11899
- DOI: https://doi.org/10.17816/PED10129-36
- ID: 11899
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Abstract
The aim of the study was to determine the capabilities of magnetic resonance morphometry and diffusion tensor imaging in the diagnosis of bilateral spastic forms of cerebral palsy in children. The main groups were 33 children aged from 1 year to 4 years 5 months. with bilateral spastic forms of cerebral palsy, the comparison group – 11 children who did not have movement disorders. The patients underwent magnetic resonance morphometry, diffusion tensor imaging. A comparison was made between the volumes of brain structures and diffusion values between groups. Significant differences (p < 0,05) were found in the volumes of the right lateral, 3rd ventricles, white matter, thalamuses, globus pallidus, putamen, hippocampus. Significant differences (p < 0,05) in diffusion values in the thalamuses and in the posterior limb of internal capsules were also identified. The correlation of the identified changes with the clinic of the disease was demonstrated. The obtained data demonstrate wide possibilities and high diagnostic value in the detection of bilateral spastic forms of cerebral palsy in children.
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##article.viewOnOriginalSite##About the authors
Viktor S. Lvov
St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Author for correspondence.
Email: viktorlvov@list.ru
Postgraduate Student of the Department of Medical Biophysics
Russian Federation, Saint PetersburgAleksandr V. Pozdnyakov
St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: Radiology@mail.ru
MD, PhD, Dr Med Sci, Professor, Head of Department of Radiology, Head of the Department of Medical Biophysics
Russian Federation, Saint PetersburgDmitry O. Ivanov
St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: Radiology@mail.ru
MD, PhD, Dr Med Sci, Professor, Rector
Russian Federation, Saint PetersburgAlexey I. Tashilkin
St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: Radiology@mail.ru
Assistant of the Department of Medical Biophysics, Radiologist of the Department of Radiology
Russian Federation, Saint PetersburgLeonid M. Makarov
St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: viktorlvov@list.ru
Associate Professor, Department of Medical Biophysics
Russian Federation, Saint PetersburgOl’ga F. Pozdnyakova
St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: Radiology@mail.ru
MD, PhD, Dr Med Sci, Radiologist of Department of Radiology, Associate Professor of the Department of Medical Biophysics
Russian Federation, Saint PetersburgTat'yana V. Melashenko
St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: Radiology@mail.ru
MD, PhD, Neurologist of Neonatal Intensive Care Unit
Russian Federation, Saint PetersburgLyubov’ B. Bessonova
Saint Olga City Children’s Hospital
Email: Radiology@mail.ru
Head, Neurological Department
Russian Federation, Saint PetersburgPavel A. Popov
Saint Olga City Children’s Hospital
Email: Radiology@mail.ru
MD, PhD, Head, MRI Unit
Russian Federation, Saint PetersburgViktoriya Yu. Aleksandrovich
St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: Radiology@mail.ru
5th year Student of Pediatric faculty
Russian Federation, Saint PetersburgReferences
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