用于局灶性和颞叶性癫痫植物调节指标

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目的：用于局灶性和颞叶性癫痫研究自主调节和自主支持的机制。

材料和方法。我们检查了对照组中的36人（19名男性和17名女性，平均年龄33.7±1.4岁）（无癫痫发作史，脑电图上癫痫样活动的患者）， 68例（32例男性和36例女性，34.1±1.5岁）患有局灶性癫痫（额叶癫痫36例，颞部癫痫32例）。对心率变异性和皮肤交感力的生理指标进行了评估。

结果。两组患者均发现了交感神经的患病率，而根据诱发的皮肤交感神经电位的分析，癫痫患者组中的超节律性自主神经活动活跃。根据颞叶癫痫患者组的相关分析结果，初始状态的特征是系统内压力增加，这反映出较高的生理成本。对数回归分析模型可基于自主神经活动支持指数将局灶性癫痫患者分为不同病程的人群。

结论。焦点性癫痫患者群体中，交感效应占主导地位，而且在营养调节的超段中心中也有很大的活动性。系统内的植物调节比率表明，系统内的压力增加，并限制了颞部患者的功能储备。癫痫一套营养指标通过逻辑回归分析法，可以将病人分为不同的焦点性癫痫群体。

作者简介

Julia Medvedeva

Ryazan State Medical University

编辑信件的主要联系方式.
Email: medvedeva_julia89@mail.ru
ORCID iD: 0000-0003-2292-6990
SPIN 代码: 9025-8780
Researcher ID: Н-1698-2018

PhD-Student of the Department of Neurology and Neurosurgery, Ryazan State Medical University

俄罗斯联邦, Ryazan

Roman Zorin

Ryazan State Medical University

Email: info@eco-vector.com
ORCID iD: 0000-0003-4310-8786
SPIN 代码: 5210-5747
Researcher ID: G-8833-2018

MD, PhD, Associate Professor of the  Department of Neurology and Neurosurgery, Ryazan State Medical University

俄罗斯联邦, Ryazan

Vladimir Zhadnov

Ryazan State Medical University

Email: info@eco-vector.com
ORCID iD: 0000-0002-5973-1196
SPIN 代码: 1632-5083
Researcher ID: A-7378-2017

MD, PhD, Professor of the Head of the Department of Neurology and Neurosurgery, Ryazan State Medical University

俄罗斯联邦, Ryazan

Michael Lapkin

Ryazan State Medical University

Email: info@eco-vector.com
ORCID iD: 0000-0003-1826-8307
SPIN 代码: 5744-5369
Researcher ID: S-2722-2016

MD, PhD, Professor, Head of the Department of Physiology with the Course of Psychophysiology, Ryazan State Medical University

俄罗斯联邦, Ryazan

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2. Fig. 1. Relationship between parameters in patients with focal temporal epilepsy

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3. Fig. 2. Relationship between parameters in patients with focal frontal epilepsy

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4. 注意：VLF，LF，HF-HRV指数，RMSD-均方根偏差，IN-张力指数，PARS-调节系统的活动参数，A1（第一阶段的振幅）和A2（第二阶段的振幅） ）-VKSP索引。实线表示正相关，虚线表示负相关 图 1颞叶局灶性癫痫患者中指标的相关关系

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5. 注意：VLF，LF，HF-HRV指数，RMSD-均方根偏差，IN-张力指数，PARS-调节系统的活动参数，A1（第一阶段的振幅）和A2（第二阶段的振幅） ）-VKSP索引。实线表示正相关，虚线表示负相关 图 2 局灶性额叶癫痫患者中指标的相关关系

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