Justification of Choice of Thromboprophylaxis Method in Patients with High-Risk Surgical Profile: A Literature Review
- Authors: Katel’nitskiy I.I.1, Nemirovich M.V.1, Prostov I.I.1, Livadnyaya E.S.1
-
Affiliations:
- Rostov State Medical University
- Issue: Vol 30, No 2 (2022)
- Pages: 279-286
- Section: Reviews
- URL: https://journals.rcsi.science/pavlovj/article/view/65252
- DOI: https://doi.org/10.17816/PAVLOVJ65252
- ID: 65252
Cite item
Abstract
INTRODUCTION: Venous thromboembolic complications (VTEC) such as deep and subcutaneous vein thrombosis and pulmonary embolism are the most important clinical problems in many specialties. High-risk factors for thrombus formation include surgical interventions leading to the activation of the hemostatic system. Despite the existing international and Russian clinical recommendations on the treatment and prophylaxis of VTEC containing a detailed description of the methods and algorithms of prophylaxis in patients with different nosologies including patients with polymorbidities, the incidence of VTEC remains high. In the scientific community, there is a continuing discussion of the effectiveness of various approaches to VTEC prophylaxis in different clinical groups of patients. Algorithms available prescribe anticoagulants at standard doses and combinations. However, in patients with comorbidities, isolated conservative anticoagulant therapy may be insufficient for effective VTEC prophylaxis.
CONCLUSION: Currently, there is a need to improve the algorithms of VTEC prophylaxis in patients with comorbid pathologies to elaborate clear indications for the use of both pharmacological and mechanical prevention methods and their combinations.
Full Text
##article.viewOnOriginalSite##About the authors
Igor’ I. Katel’nitskiy
Rostov State Medical University
Email: katelnizkji@mail.ru
ORCID iD: 0000-0002-3745-9064
SPIN-code: 3583-6234
MD, Dr. Sci. (Med.), Professor
Russian Federation, Rostov-on-DonMaksim V. Nemirovich
Rostov State Medical University
Author for correspondence.
Email: nemiroich.maxim@yandex.ru
ORCID iD: 0000-0002-3797-4007
SPIN-code: 4558-4041
Russian Federation, Rostov-on-Don
Igor’ I. Prostov
Rostov State Medical University
Email: igor-prostov@mail.ru
ORCID iD: 0000-0002-7853-6775
SPIN-code: 5706-3190
MD, Cand. Sci. (Med.)
Russian Federation, Rostov-on-DonEkaterina S. Livadnyaya
Rostov State Medical University
Email: livadnyaya@mail.ru
ORCID iD: 0000-0002-1148-1044
SPIN-code: 2252-5492
MD, Cand. Sci. (Med.)
Russian Federation, Rostov-on-DonReferences
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