Test with external peripheral vascular occlusion in evaluation of ergoreflex in patients with chronic obstructive pulmonary disease

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Abstract

Aim. To evaluate changes in the cardiointervalogram (CIG) in the test with external peripheral vascular occlusion in patients with chronic obstructive pulmonary disease (COPD) and in individuals without diseases of the respiratory system.

Materials and Methods. The study included 105 men, of them 64 patients with COPD (age 64.98±8.67) and 41 volunteers without diseases of the respiratory system (age 61.68±9.21). The autonomic status was examined and alterations in CIG in the test with occlusion were evaluated on Varicard hardware and software complex (OOO Ramena, Russia).

Results. The obtained data showed the autonomic imbalance with predomination of the activity of sympathetic division of the autonomic nervous system (ANS) in patients with COPD as compared to the control group (p<0.05). A study of ergoreflex by analysis of changes in CIG showed reduction of the activity of sympathetic division of the ANS in the test with external peripheral vascular occlusion in individuals without diseases of  the respiratory system. In patients with COPD, changes in CIG in the test were less expressed and not always achieved statistically significant level (p>0.05).

Conclusions. Differences in the results of the test with external peripheral vascular occlusion in patients with COPD and volunteers without diseases of the respiratory system are attributed to hyperactivation of ergofeflex in patents with COPD.

About the authors

Aleksey V. Kosyakov

Ryazan State Medical University

Author for correspondence.
Email: Kosyakov_alex@rambler.ru
ORCID iD: 0000-0001-6965-5812
SPIN-code: 8096-5899
ResearcherId: X-2649-2018

Assistant of the Department of Hospital Therapy with the Course of Medico-social Examination

Russian Federation, 390026 g. Ryazan', ul. Vysokovol'tnaya, d. 9

Vladimir N. Abrosimov

Ryazan State Medical University, Ryazan

Email: Kosyakov_alex@rambler.ru
ORCID iD: 0000-0001-7011-4765
SPIN-code: 3212-4620
ResearcherId: S-2818-2016

MD, PhD, Professor, Head of the Department of Therapy and Family Medicine of Post-graduate Education Faculty with the Course of Medico-social Examination

Russian Federation, 390026 g. Ryazan', ul. Vysokovol'tnaya, d. 9

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Copyright (c) 2020 Kosyakov A.V., Abrosimov V.N.

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