评估应用前列腺素类似物的原发性开角型青光眼患者的视网膜厚度和白内障术后囊性黄斑水肿发生率

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目标: 评估前列腺素类似物和非甾体抗炎药对原发性开角型青光眼患者在进行超声乳化术并植入人工晶状体后的视网膜中央凹厚度和白内障术后囊性黄斑水肿发展的影响。

材料和方法: 共有91名患者被纳入研究。第一和第二观察组包括各22名应用前列腺素类似物的患者（22只眼睛）。对照组包括47名患者(57只眼睛)，不伴有青光眼。各组受试者术后都接受了皮质类固醇和抗生素，而第二组和对照组的患者还接受了非甾体类抗炎药。通过光学相干断层扫描来评估术前、术后2周、2个月和6个月视网膜中央区的厚度。

结果: 观察组中超声乳化术后视网膜中央凹的厚度增加，第一组在6个月后恢复到基线值，第二组在2个月后恢复到基线值，对照组在术后2周低于术前值，然后逐渐增加，但没有达到基线值。

结论: 在我们对应用前列腺素类似物患者进行超声乳化术和人工晶状体植入术后没有发现白内障术后囊性黄斑水肿。术后使用非甾体类抗炎药可以稳定视网膜的厚度，有助于恢复其正常厚度。

作者简介

Xiaoyuan Wang

Pavlov First St. Petersburg State Medical University

Email: wangxiaoyuan20121017@gmail.com
ORCID iD: 0000-0002-1135-6796

PhD student

俄罗斯联邦, 6–8 L’va Tolstogo str., Saint Petersburg, 197022

Sergey Yu. Astakhov

Pavlov First St. Petersburg State Medical University

Email: astakhov73@mail.ru
ORCID iD: 0000-0003-0777-4861
SPIN 代码: 7732-1150
Scopus 作者 ID: 56660518500

Dr. Sci. (Med.), professor

俄罗斯联邦, 6–8 L’va Tolstogo str., Saint Petersburg, 197022

Vitaly V. Potemkin

City Multidiscipline Hospital No. 2

Email: potem@inbox.ru
ORCID iD: 0000-0001-7807-9036
SPIN 代码: 3132-9163

Cand. Sci. (Med.)

俄罗斯联邦, 5 Uchebniy pereulok, Saint Petersburg, 194354

Albina R. Potemkina

City Multidiscipline Hospital No. 2

Email: prinzabiyka@mail.ru

ophthalmologist

俄罗斯联邦, 5 Uchebniy pereulok, Saint Petersburg, 194354

Liliya K. Anikina

Pavlov First St. Petersburg State Medical University

编辑信件的主要联系方式.
Email: lily-sai@yandex.ru
ORCID iD: 0000-0001-8794-0457

medical resident

俄罗斯联邦, 6–8 L’va Tolstogo str., Saint Petersburg, 197022

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2. 图.1.比较各组在不同观察期视网膜中央凹厚度的动态变化 Fig. 1. Dynamics of foveal thickness at different follow-up periods in groups

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3. 图.2.比较各组不同观察期视网膜中央厚度与基线差异的动态变化 Fig. 2. Dynamics of the difference from the initial level of foveal thickness at different follow-up periods of observation in groups

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版权所有 © Wang X., Astakhov S., Potemkin V., Potemkina A., Anikina L., 2021

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