Von Hippel–Lindau disease with concomitant Hodgkin’s disease and congenital hypertrophy of the retinal pigment epithelium
- 作者: Rakitsky A.1, Shakhnazarova A.1, Shcherba M.1
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隶属关系:
- Diagnostic Center Nо. 7 (Ophthalmological) for Adults and Children
- 期: 卷 13, 编号 1 (2020)
- 页面: 87-90
- 栏目: Case reports
- URL: https://journals.rcsi.science/ov/article/view/25753
- DOI: https://doi.org/10.17816/OV25753
- ID: 25753
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The article presents a rare case of combination of von Hippel–Lindau disease and Hodgkin’s disease. The disease began with neurological symptoms with gradual progression over the next 3 years. The diagnosis of von Hippel–Lindau disease was made after MRI of brain and spinal cord, abdominal MICTs, and detection of brain stem and spinal cord tumors, multiple pancreatic cysts. We performed resection trepanation of the posterior cranial fossa and microsurgical total removal of hemangioblastoma of the medulla oblongata. After 1.5 years the patient is diagnosed with Hodgkin’s disease and several courses of chemotherapy are carried out, reaching full remission, confirmed by PET with CT. 14 months later, the patient consulted an ophthalmologist due to visual impairment and floating opacities in her left eye. The ophthalmologic examination for the first time revealed multiple bilateral retinal hemangiomas and vitreal hemorrhages from tractional retinal tears caused by posterior hyaloid detachment and unrelated to hemangiomas in the left eye. The barrier laser coagulation of the left eye retinal tears was performed, and the observation tactics was adopted.
作者简介
Aleksandr Rakitsky
Diagnostic Center Nо. 7 (Ophthalmological) for Adults and Children
编辑信件的主要联系方式.
Email: avr72@list.ru
Head of the Laser Department
俄罗斯联邦, Saint PetersburgAida Shakhnazarova
Diagnostic Center Nо. 7 (Ophthalmological) for Adults and Children
Email: aida66@bk.ru
Candidate of Medical Sciences, Head of the Department of Retinal Pathology
俄罗斯联邦, Saint PetersburgMarina Shcherba
Diagnostic Center Nо. 7 (Ophthalmological) for Adults and Children
Email: sherba.v@yandex.ru
Ophthalmic Surgeon, laser department
俄罗斯联邦, Saint Petersburg参考
- D’hondt R, Thomas J, Van Oosterom AT, Dewolf-Peeters C. Hodgkin’s disease in a patient with von Hippel – Lindau disease. A case report. Acta Clin Belg. 2000;55(5):276-278. https://doi.org/10.1080/17843286.2000.11754310.
- Lou LH, Shen H, Lin J, et al. T-cell lymphoma with von Hippel–Lindau disease: a rare case report and review of literature. Int J Clin Exp Pathol. 2015;8(5):5837-5843.
- Лазерная хирургия сосудистой патологии глазного дна / Под ред. А.Г. Щуко. – М.: Офтальмология, 2014. – 250 с. [Lazernaya khirurgiya sosudistoy patologii glaznogo dna. Ed. by A.G. Shchuko. Moscow: Oftal’mologiya; 2014. 250 р. (In Russ.)]
- Wong WT, Liang KJ, Hammel K, et al. Intravitreal ranibizumab therapy for retinal capillary hemangioblastoma related to von Hippel – Lindau disease. Ophthalmology. 2008b;(115):1957-1964. https://doi.org/10.1016/j.ophtha.2008.04.033.
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