Myelinated retinal nerve fibers associated with retinal vascular abnormalities and retino-vitreal neovascularization complicated by recurrent vitreous hemorrhage (clinical case)

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详细

Myelinated retinal nerve fibres are a rare, benign and asymptomatic lesion that is detected incidentally at fundus examination. In some cases, they may be associated with various abnormalities of the eye or have a complicated course. The article presents a clinical case of myelinated retinal nerve fibers associated with retinal vascular abnormalities and retino-vitreal neovascularization complicated by recurrent vitreous hemorrhage.

作者简介

Anastasiya Panfilova

Ophthalmological center “Vision”

Email: panfilova@zrenie.spb.ru
ORCID iD: 0000-0002-8191-6090

ophthalmologist

俄罗斯联邦, Saint Petersburg

Taisiia Doktorova

S. Fyodorov Eye Microsurgery Federal State Institution, Saint Petersburg Branch; North-Western State Medical University named after I.I. Mechnikov

编辑信件的主要联系方式.
Email: taisiiadok@mail.ru
ORCID iD: 0000-0003-2162-4018
SPIN 代码: 8921-9738

postgraduate student, ophthalmologis

俄罗斯联邦, Saint Petersburg; Saint Petersburg

Aleksei Suetov

S. Fyodorov Eye Microsurgery Federal State Institution, Saint Petersburg Branch; State Scientific Research Test Institute of Military Medicine

Email: ophtalm@mail.ru
ORCID iD: 0000-0002-8670-2964
SPIN 代码: 4286-6100

МD, Cand. Sci. (Med.), ophthalmologist, senior research associate

俄罗斯联邦, Saint Petersburg; Saint Petersburg

参考

  1. Shelton JB, Digre KB, Gilman J, et al. Characteristics of myelinated retinal nerve fiber layer in ophthalmic imaging: Findings on autofluorescence, fluorescein angiographic, infrared, optical coherence tomographic, and red-free images. Arch Ophthalmol. 2013;131(1):107–109. doi: 10.1001/jamaophthalmol.2013.560
  2. Straatsma BR, Foos RY, Heckenlively JR, Taylor GN. Myelinated retinal nerve fibers. Am J Ophthalmol. 1981;91(1):25–38. doi: 10.1016/0002-9394(81)90345-7
  3. Jean-Louis G, Katz BJ, Digre KB, et al. Acquired and progressive retinal nerve fiber layer myelination in an adolescent. Am J Ophthalmol. 2000;130(3):361–362. doi: 10.1016/S0002-9394(00)00550-X
  4. Ali BH, Logani S, Kozlov KL, et al. Progression of retinal nerve fiber myelination in childhood. Am J Ophthalmol. 1994;118(4):515–517. doi: 10.1016/S0002-9394(14)75805-2
  5. Fasiuddin KJ. Ocular findings associated with myelinated retinal nerve fibers. Cureus. 2021;13(4): e14552. doi: 10.7759/cureus.14552
  6. Berry-Brincat A, Shafquat S. Myelinated nerve fibres: a rare cause of recurrent vitreous haemorrhage. Eye. 2008;22:165–167. doi: 10.1038/sj.eye.6703002
  7. Hildebrand C, Remahl S, Persson H, Bjartmar C. Myelinated nerve fibres in the CNS. Prog Neurobiol. 1993;40(3):319–384. doi: 10.1016/0301-0082(93)90015-K
  8. Hunter SF, Leavitt JA, Rodriguez M. Direct observation of myelination in vivo in the mature human central nervous system. A model for the behaviour of oligodendrocyte progenitors and their progeny. Brain. 1997;120(11):2071–2082. doi: 10.1093/BRAIN/120.11.2071
  9. Fitzgibbon T, Nestorovski Z. Morphological consequences of myelination in the human retina. Exp Eye Res. 1997;65(6):809–819. doi: 10.1006/exer.1997.0388
  10. Tarabishy AB, Alexandrou TJ, Traboulsi EI. Syndrome of myelinated retinal nerve fibers, myopia, and amblyopia: a review. Surv Ophthalmol. 2007;52(6):588–596. doi: 10.1016/j.survophthal.2007.08.016
  11. Silvestri G, Sehmi K, Hamilton P. Retinal vascular abnormalities. A rare complication of myelinated nerve fibers? Retina. 1996;16(3):214–218. doi: 10.1097/00006982-199616030-00005
  12. Leys AM, Leys MJ, Hooymans JMM, et al. Myelinated nerve fibers and retinal vascular abnormalities. Retina. 1996;16(2):89–96. DOI: 1097/00006982-199616020-00001
  13. Minning CA, Davidorf FH. Neovascularization associated with myelinated nerve fibers: a case report. Ann Ophthalmol. 1983;15(12):1142–1144.

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2. Fig. 1. Color fundus photography of a patient with myelinated nerve fibers complicated by vascular abnormalities (explanations in the text): a — general view, resolving vitreous hemorrhage (black arrows), laser burns after panretinal photocoagulation (blue arrows); b — myelinated retinal nerve fibers area with retino-vitreal neovascularization (arrow); c — structural OCT scan through the corresponding area; d, e — horizontal and vertical structural OCT scans through the center of the macula, in the fovea lamellar hole, epiretinal fibrosis, myelinated retinal nerve fibers extending into the fovea

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3. Fig. 2. Retinal fluorescein angiography data of a female patient with myelinated retinal fibers complicated by vascular abnormalities (explanations in the text): a — fundus image; b–d — hyperfluorescence of a fine, microvascular network with telangiectasias and neovascularization with signs of leakage in the late venous phase

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4. Fig. 3. Retinal fluorescein angiography data of the female patient with myelinated retinal fibers complicated by vascular abnormalities 3 months after intravitreal injection of ranibizumab (explanations in the text): a — fundus image; b–d — partial regression of the neovascularization and reduction of leakage

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