Cytomegalovirus uveitis in HIV-infected people: possible complications

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BACKGROUND: Cytomegalovirus uveitis is an AIDS-marker disease. If typical chorioretinal foci associated with cytomegalovirus viremia, inflammatory diseases of cytomegalovirus etiology of other organs are detected, etiotropic treatment and antiretroviral therapy are prescribed. Later on, the patient continues to be monitored by an ophthalmologist.

AIM: The aim is to identify the structure of complications, the frequency and the timing of their occurrence in cytomegalovirus uveitis in HIV-infected patients, the relationship with the treatment.

MATERIALS AND METHODS: The study was performed at the St. Petersburg Center for the Prevention and Control of AIDS and Infectious Diseases and the Department of Ophthalmology of the North-Western State Medical University named after I.I. Mechnikov. The study group consisted of 66 patients (97 eyes).

RESULTS: The development of complications of the disease was detected in 86.6% of patients. In patients, following complications were reported: retinal detachment, complicated cataract, partial optic nerve atrophy, cystoid macular edema, and secondary exotropia.

CONCLUSION: Cytomegalovirus uveitis in HIV-infected patients has a predominantly complicated course.

作者简介

Tatiana Sizova

Saint Petersburg Center for Control of AIDS and Infectious Diseases; North-Western State Medical University named after I.I. Mechnikov

编辑信件的主要联系方式.
Email: tanja_sizova@list.ru
ORCID iD: 0000-0003-4089-1242
SPIN 代码: 2939-5495

Ophthalmologist, Postgraduate Student

俄罗斯联邦, Saint Petersburg; Saint Petersburg

Valentina Khokkanen

North-Western State Medical University named after I.I. Mechnikov

Email: valentina.khokkanen@szgmu.ru
ORCID iD: 0000-0001-8096-5088
SPIN 代码: 6536-4889

Dr. Sci. (Med.), Professor, Professor of Ophthalmology Department

俄罗斯联邦, Saint Petersburg

Natalia Zumbulidze

North-Western State Medical University named after I.I. Mechnikov

Email: guramovna@gmail.com
ORCID iD: 0000-0002-7729-097X
SPIN 代码: 4439-8855

Cand. Sci. (Med.), Associate Professor of Ophthalmology Department

俄罗斯联邦, Saint Petersburg

参考

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2. Fig. 1. Fundus photoregistration of a patient. Paleness of the temporal half of the optic nerve head (arrow)

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3. Fig. 2. Structure of retinal detachments in cytomegalovirus uveitis

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4. Fig. 3. Optical coherence tomogram of a patient. Cystoid macular edema, epiretinal membrane (arrows)

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版权所有 © Sizova T., Khokkanen V., Zumbulidze N., 2022

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