Diagnosis and treatment of fungal keratitis. Part I
- 作者: Skryabina Y.1, Astakhov Y.2, Konenkova Y.1, Kasymov F.1, Zumbulidze N.3, Varganova T.1, Petukhov V.1, Pirgunova A.3, Masian J.3, Klimko N.3, Bogomolova T.3, Desyatik E.3
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隶属关系:
- City Multi-Field Hospital No 2
- I.P. Pavlov State Medical University of St. Petersburg
- North-Western State Medical University n.a. I.I. Mechnikov
- 期: 卷 11, 编号 3 (2018)
- 页面: 63-73
- 栏目: Articles
- URL: https://journals.rcsi.science/ov/article/view/10542
- DOI: https://doi.org/10.17816/OV11363-73
- ID: 10542
如何引用文章
详细
Fungal keratitis (FK) is a difficult diagnostic challenge for ophthalmologists.
The aim is to familiarize practicing physicians with the diagnostic algorithm worked out in the Ophthalmological Center of SPB City hospital No. 2 using modern research methods, and to assess the epidemiology of fungal keratitis in the North-West Region.
Materials and methods. Patients underwent laboratory diagnostics (fluorescence microscopy of corneal scrapings from the cornea, сulture on Sabouraud agar and broth), confocal in vivo microscopy, optical coherence tomography.
Results. During the period from 2007 to 2017, 41 cases of FK were identified in the City hospital No. 2, of which filamentous fungi were the causative agent in 32 cases (78%), yeast fungi — in 9 cases (22%). Our analysis included patients with fungal keratitis over the past three years, all of them underwent a full diagnostic cycle. Filamentous fungi were found among 12 of them (63%), yeast — in 7 (37%). Our data, considering the statistics of fungal keratitis in the North-West of Russia — a region with a high level of urbanization and industrialization, and located in the temperate zone — showed a predominance of filamentous fungi as pathogens (prevalence 1.3 times higher). Our scheme of keratitis diagnostics — confocal in vivo microscopy, OCT, fungal culture — is a reliable way to identify fungal pathogens in the cornea, and can be recommended for use in practical ophthalmology.
作者简介
Yelena Skryabina
City Multi-Field Hospital No 2
编辑信件的主要联系方式.
Email: scryabelena@mail.ru
MD, ophthalmologist, Microsurgery Department No 4
俄罗斯联邦, Saint PetersburgYuriy Astakhov
I.P. Pavlov State Medical University of St. Petersburg
Email: astakhov73@mail.ru
MD, Doctor of Medical Science, Professor. Department of Ophthalmology
俄罗斯联邦, Saint PetersburgYanina Konenkova
City Multi-Field Hospital No 2
Email: Krocon@mail.ru
MD, Head of Department, Microsurgery Department No 4
俄罗斯联邦, Saint PetersburgFarkhod Kasymov
City Multi-Field Hospital No 2
Email: farkkas@yahoo.com
MD, PhD, Assistant Professor, Ophthalmology Department
俄罗斯联邦, Saint PetersburgNataliya Zumbulidze
North-Western State Medical University n.a. I.I. Mechnikov
Email: zumbulenok@mail.ru
MD, PhD, Assistant Professor, Ophthalmology Department
俄罗斯联邦, Saint PetersburgTatiana Varganova
City Multi-Field Hospital No 2
Email: Varganova.ts@yandex.ru
MD, Candidate of Medical Sciences, ophthalmologist, Consultative-Diagnostic Department of Ophthalmology
俄罗斯联邦, Saint PetersburgVladimir Petukhov
City Multi-Field Hospital No 2
Email: v.p.petukhov@gmail.com
MD, Ophthalmologist, Department of Laser Microsurgery
俄罗斯联邦, Saint PetersburgAlyona Pirgunova
North-Western State Medical University n.a. I.I. Mechnikov
Email: cvcv4698@yandex.ru
Second Year Ophthalmology Resident. Department of Ophthalmology
俄罗斯联邦, Saint PetersburgJanek Masian
North-Western State Medical University n.a. I.I. Mechnikov
Email: phaser.j@gmail.com
Second Year Ophthalmology Resident. Department of Ophthalmology
俄罗斯联邦, Saint PetersburgNikolai Klimko
North-Western State Medical University n.a. I.I. Mechnikov
Email: n_klimko@mail.ru
MD, Doctor of Medical Science, Professor, Head of the Department of Clinical Mycology, Allergology and Immunology
俄罗斯联邦, Saint PetersburgTatyana Bogomolova
North-Western State Medical University n.a. I.I. Mechnikov
Email: tatiyna.bogomolova@szgmu.ru
Head of the Research Laboratory of Mycological Monitoring and Fungal Biology of the P.N. Kashkin
俄罗斯联邦, Saint Petersburg, RussiaEkaterina Desyatik
North-Western State Medical University n.a. I.I. Mechnikov
Email: e_desyatik@mail.ru
allergologist-immunologist of the Mycological Department of the P.N. Kashkin Research Institute of Medical Mycology
俄罗斯联邦, Saint Petersburg参考
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