The influence of some general diseases for changes on the ocular surface after trabeculectomy
- Authors: Аntonova А.V.1,2, Nikolaenko V.P.1,2, Brzheskiy V.V.3, Vuks A.J.4, Koskin S.A.5,6
-
Affiliations:
- Saint Petersburg Multifield Hospital No. 2
- Saint Petersburg State University
- Saint Petersburg State Pediatric Medical University
- V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology
- Kirov Military Medical Academy
- Pavlov Institute of Physiology of the Russian Academy of Sciences
- Issue: Vol 17, No 1 (2024)
- Pages: 7-20
- Section: Original researches
- URL: https://journals.rcsi.science/ov/article/view/255189
- DOI: https://doi.org/10.17816/OV568993
- ID: 255189
Cite item
Abstract
BACKGROUND: By now, possible effects of diabetes mellitus and arterial hypertension on the ocular surface changes after trabeculectomy have not been evaluated.
AIM: Analysis of the effects of arterial hypertension therapy and diabetes mellitus on the ocular surface changes after trabeculectomy.
MATERIALS AND METHODS: The study group consisted of 443 patients, including those with arterial hypertension (179 patients), non insulin dependent compensated type 2 diabetes mellitus (25 patients) and their combination (53 persons), operated in 2016–2020 in the City Multifield Hospital No. 2, Saint-Petersburg, for primary open-angle noncompensated glaucoma and then observed for 6 to 24 months. The dynamics of ocular surface disease index (OSDI), tear film break-up time (TBUT), and amount of total tear production has been studied.
RESULTS: The probability of the trabeculectomy success did not depend on the concomitant comorbidity. In contrast to intraocular pressure, the criteria for subjective and objective assessment of the ocular surface state were not subject to such obvious changes. In diabetic patients, the studied criteria have not changed compared to the baseline.
CONCLUSIONS: The mentioned systemic diseases do not influence the state of the ocular surface in patients with glaucoma, and are not an independent risk factor for the failure of the IOP-lowering surgical procedure. The presence of diabetes mellitus prevents the accompanying a successful trabeculectomy regression of symptoms and clinical and functional signs of dry eye disease.
Full Text
##article.viewOnOriginalSite##About the authors
Аnastasiia V. Аntonova
Saint Petersburg Multifield Hospital No. 2; Saint Petersburg State University
Author for correspondence.
Email: dr.antonova.av@gmail.com
ORCID iD: 0000-0002-2639-2765
SPIN-code: 2166-3936
Ophthalmologist
Russian Federation, 5 Uchebnyi lane, Saint Petersburg, 194354; 7–9 Universitetskaya embankment, Saint Petersburg, 199034Vadim P. Nikolaenko
Saint Petersburg Multifield Hospital No. 2; Saint Petersburg State University
Email: dr.Nikolaenko@mail.ru
ORCID iD: 0000-0002-6393-1289
SPIN-code: 4906-2542
MD, PhD, Doc. Sci. (Med.), Head of Ophthalmology Department, professor Otorhinolaryngology and ophthalmologydepartment
Russian Federation, 5 Uchebnyi lane, Saint Petersburg, 194354; 7–9 Universitetskaya embankment, Saint Petersburg, 199034Vladimir V. Brzheskiy
Saint Petersburg State Pediatric Medical University
Email: vvbrzh@yandex.ru
ORCID iD: 0000-0001-7361-0270
SPIN-code: 5442-0989
MD, Dr. Sci. (Med.), Professor
Russian Federation, Saint PetersburgAlexandr Ja. Vuks
V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology
Email: ayavuks@bekhterev.ru
ORCID iD: 0000-0002-6700-0609
SPIN-code: 2290-4021
Russian Federation, Saint Petersburg
Sergey A. Koskin
Kirov Military Medical Academy; Pavlov Institute of Physiology of the Russian Academy of Sciences
Email: eyemillenium@mail.ru
ORCID iD: 0000-0003-3994-9232
SPIN-code: 9882-6880
Dr. Sci. (Medicine), Professor
Russian Federation, Saint Petersburg; Saint PetersburgReferences
- Goebbels M. Tear secretion and tear film function in insulin dependent diabetics. Br J Ophthalmol. 2000;84(1):19–21. doi: 10.1136/bjo.84.1.19
- Lv H, Li A, Zhang X, et al. Meta-analysis and review on the changes of tear function and corneal sensitivity in diabetic patients. Acta Ophthalmol. 2014;92(2):e96–e104. doi: 10.1111/aos.12063
- Dogru M, Katakami C, Inoue M. Tear function and ocular surface changes in noninsulin-dependent diabetes mellitus. Ophthalmology. 2001;108(3):586–592. doi: 10.1016/s0161-6420(00)00599-6
- Ferrero A, Alassane S, Binquet C, et al. Dry eye disease in the elderly in a French population-based study (the Montrachet study: Maculopathy, Optic Nerve, nuTRition, neurovAsCular and HEarT diseases): Prevalence and associated factors. Ocul Surf. 2018;16(1):112–119. doi: 10.1016/j.jtos.2017.09.008
- Millán A, Viso E, Gude F, et al. Incidence and risk factors of dry eye in a Spanish adult population: 11-year follow-up from the Salnes Eye Study. Cornea. 2018;37(12):1527–1534. doi: 10.1097/ICO.0000000000001713
- Bron AJ, de Paiva CS, Chauhan SK, et al. TFOS DEWS II pathophysiology report. Ocul Surf. 2017;15(3):438–510. doi: 10.1016/j.jtos.2017.05.011
- Wong J, Lan W, Ong LM, Tong L. Non-hormonal systemic medications and dry eye. Ocul Surf. 2011;9(4):212–226. doi: 10.1016/s1542-0124(11)70034-9
- Fraunfelder FT, Sciubba JJ, Mathers WD. The role of medications in causing dry eye. J Ophthalmol. 2012;2012:285851. doi: 10.1155/2012/285851
- Pérez-Bartolomé F, Martínez-de-la-Casa JM, Arriola-Villalobos P, et al. Ocular surface disease in patients under topical treatment for glaucoma. Eur J Ophthalmol. 2017;27(6):694–704. doi: 10.5301/ejo.5000977
- Antonova AV, Nikolaenko VP, Brzheskiy VV. Realization of a cascade treatment algorithm for glaucoma in Saint Petersburg. Russian Journal of Clinical Ophthalmology. 2021;21(3):123–128. EDN: UJLIYJ doi: 10.32364/2311-7729-2021-21-3-123-128
- Erichev VP, Petrov SYu, Antonov AA, Volzhanin AV. International standards of clinical trials in glaucoma surgery. National Journal glaucoma. 2016;15(2):102–108. EDN: WJGTUN
- Shaarawy T, Grehn F, Sherwood M, editors. Guidelines on design and reporting of glaucoma surgical trials. World Glaucoma Association Amsterdam: Kugler Publications, 2009. 83 p.
- Egorov EA, Erichev VP, Onishchenko AL, et al. Systemic risk factors for developing of primary open-angle glaucoma. Russian journal of clinical ophthalmology. 2018;18(3):140–145. EDN: XYMTED doi: 10.21689/2311-7729-2018-18-3-140-145
- Kazanova SYu. Evaluation of the main factors of progression of primary glaucoma [dissertation]. Yaroslavl, 2020. Available from: https://www.dissercat.com/content/otsenka-osnovnykh-faktorov-progressirovaniya-pervichnoi-glaukomy/read [cited: 2023 Sep 2]. (In Russ.)
- Kuroyedov AV, Movsisyan AB, Egorov EA, et al. The profile of patients with primary open-angle glaucoma in the Russian Federation. National Journal glaucoma. 2021;20(1):3–15. EDN: MJTOCP doi: 10.25700/NJG.2021.01.01
- Kuroyedov AV, Movsisyan AB, Egorov EA, et al. The profile of patients with primary open-angle glaucoma in the Russian Federation (preliminary results of a multicenter population-based study). Part 2. National Journal glaucoma. 2021;20(2):31–42. EDN: WKYRWJ doi: 10.53432/2078-4104-2021-20-2-31-42
- Salim S, Shields MB. Glaucoma and systemic diseases. Surv Ophthalmol. 2010;55(1):64–77. doi: 10.1016/j.survophthal.2009.03.006
- Wang T-J, Wang I-J, Hu C-C, Lin H-C. Comorbidities of dry eye disease: a nationwide population-based study. Acta Ophthalmol. 2012;90(7):663–668. doi: 10.1111/j.1755-3768.2010.01993.x
- Zhang X, Zhao L, Deng S, et al. Dry eye syndrome in patients with diabetes mellitus: prevalence, etiology, and clinical characteristics. J Ophthalmol. 2016;2016:8201053. doi: 10.1155/2016/8201053
- Dana R, Bradley JL, Guerin A, et al. Comorbidities and prescribed medications in patients with or without dry eye disease: A population-based study. Am J Ophthalmol. 2019;198:181–192. doi: 10.1016/j.ajo.2018.10.001
- Yoo TK, Oh E. Diabetes mellitus is associated with dry eye syndrome: a meta-analysis. Int Ophthalmol. 2019;39(11):2611–2620. doi: 10.1007/ s10792-019-01110-y
- Chamard C, Larrieu S, Baudouin C, et al. Preservative-free versus preserved glaucoma eye drops and occurrence of glaucoma surgery. A retrospective study based on the French National Health Insurance Information System, 2008–2016. Acta Ophthalmol. 2020;98(7): e876–e881. doi: 10.1111/aos.14410
- Kobalava ZhD, Konradi AO, Nedogoda SV, et al. Arterial hypertension in adults. Clinical guidelines 2020. Russian Journal of Cardiology. 2020;25(3):3786. EDN: TCRBRB doi: 10.15829/1560-4071-2020-3-3786
- Dedov II, Shestakova MV, Vikulova OK, et al. Diabetes mellitus in Russian Federation: prevalence, morbidity, mortality, parameters of glycaemic control and structure of glucose lowering therapy according to the Federal Diabetes Register, status 2017. Diabetes mellitus. 2018;21(3):144–159. EDN: XYEBET doi: 10.14341/DM9686
- Erb C, Gast U, Schremmer D. German register for glaucoma patients with dry eye. I. Basic outcome with respect to dry eye. Graefes Arch Clin Exp Ophthalmol. 2008;246:1593–1601. doi: 10.1007/s00417-008-0881-9
- Dave A, Bali SJ, Sharma R, et al. Prevalence of diabetes mellitus and hypertension among Indian glaucoma patients and evaluation of systemic therapy. Int Ophthalmol. 2013;33(5):527–532. doi: 10.1007/s10792-013-9737-3
- Zhao Y, Fu J-L, Li Y-L, et al. Epidemiology and clinical characteristics of patients with glaucoma: An analysis of hospital data between 2003 and 2012. Indian J Ophthalmol. 2015;63(11):825–831. doi: 10.4103/0301-4738.171963
- Kawashima M, Yamada M, Shigeyasu C, et al. Association of systemic comorbidities with Dry Eye Disease. J Clin Med. 2020;9(7):2040. doi: 10.3390/jcm9072040
- Antonova AV, Nikolaenko VP, Brzheskiy VV, Vuks AJ. Factors influencing the effectiveness of trabeculectomy: following materials of the City Multidisciplinary Hospital No. 2. Ophthalmology Reports. 2022;15(4):35–44. EDN: TRIJLV doi: 10.17816/OV159363
- Antonova AV, Nikolaenko VP, Brzheskiy VV, Vuks AJ. Effect of gender on the ocular surface after trabeculectomy. Russian Journal of Clinical Ophthalmology. 2023;23(3):136–145. EDN: CMVRSZ doi: 10.32364/2311-7729-2023-23-3-5