The method of the exophthalmos value predicted calculation when planning the orbital decompression procedure in patients with endocrine ophthalmopathy

Cover Page

Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription Access

Abstract

BACKGROUND: The most effective method of surgical treatment of lipogenic and mixed forms of edematous exophthalmos is currently the internal orbital decompression. During this surgical procedure, the excessive pathologically altered adipose tissue is removed from the external and the internal surgical spaces of the orbit. Many scientists are developing methods for calculating the volume of orbital fat, but the question on developing a method for predicted exophthalmos after internal orbital decompression, which could be used without attracting additional equipment and software, is easy to learn and does not require a long calculation time, remains actual. This method has to take into account the individual features of the patient’s orbital structure and be used for calculations in the bilateral proptosis correction.

AIM: To develop and evaluate the effectiveness of a new method for calculating the eyeball position after orbital decompression.

MATERIALS AND METHODS: 64 patients (126 orbits) with lipogenic and mixed forms of endocrine ophthalmopathy were examined. All patients underwent internal orbital decompression, during which the orbital fat was removed, the volume of which was calculated according to the developed original method. Patients underwent ophthalmological examination and MSCT before surgery and 6 months after it. .

RESULTS: As a result of orbital decompression in the examined group, a decrease in proptosis was observed in all patients, and the exophthalmos calculated by the method corresponded to the eyeball position in patients in 6 months after surgery. The level of statistical significance of the planned postoperative eyeball position in relation to the actual postoperative exophthalmos calculated according to the Student’s t-test was 0.98 (p > 0.05), that is, it can be argued that the groups do not differ, and no statistically significant differences were found.

CONCLUSIONS: The developed method for calculating the estimated postoperative exophthalmos is effective without using additional software. This technique allows you to achieve a symmetrical eyeball position in the postoperative period and to reduce the risk of complications.

About the authors

Dmitrii V. Davydov

Peoples’ Friendship University of Russia; A.I. Evdokimov Moscow State University of Medicine and Dentistry

Email: d-davydov3@yandex.ru
ORCID iD: 0000-0001-5506-6021
SPIN-code: 1368-2453

Dr. Sci. (Med.), Professor, head of Department of Reconstructive and Plastic Surgery with an Ophthalmology Course

Russian Federation, 8, Miklukho-Maklaja street, Moscow,117198; Moscow

Dmitrii Anatolevich Lezhnev

A.I. Evdokimov Moscow State University of Medicine and Dentistry

Email: lezhnevd@mail.ru

Dr. Sci. (Med.), Professor, head of Department of Radiology

Russian Federation, Miklukho-Maklaja street, 8, Moscow, 117198

Konstantin A. Konovalov

1586 Military clinical hospital

Author for correspondence.
Email: kkonovalov82@mail.ru

Head of the ophthalmological Department

Russian Federation, Mashtakova street 4, Podolsk, Moscow region, 142110

References

  1. Saakyan SV, Panteleeva OG, Sirmays OS. Clinical features of endocrine ophthalmopathy in children. Russian Pediatric Ophthalmology. 2014;9(3):20–23. (In Russ.)
  2. Brovkina AF, Stoyukhlna AS. Classification of endocrine ophthalmopathy. Problems of Endocrinology. 2006;52(5):11–15. (In Russ.)
  3. Davydov DV, Lezhnev DA, Konovalov KA, et al. New method of calculating the excess amount of soft tissues of the orbit in patients with endocrine ophthalmopathy when planning operations. Ophthalmology in Russia. 2019;16(4):442–448. (In Russ.) doi: 10.18008/1816-5095-2019-4-442-448
  4. Kochetkov PA, Savvateeva DM, Lopatin AS. Orbital decompression: review of surgical approaches and analyse of effective. Russian Rhinology. 2013;21(1):28–34. (In Russ.)
  5. Brovkina AF. Sovremennye aspekty patogeneza i lecheniya ehndokrinnoi oftal’mopatii. Vestnik Rossijskoj Akademii nauk. 2003;73(5):52–54. (In Russ.)
  6. Kazim M, Trokel SL, Acaroglu G, Elliott A. Reversal of dysthyroid optic neuropathy following orbital fat decompression. Br J Ophthalmol. 2000;84(6):600–605. doi: 10.1136/bjo.84.6.600
  7. Comerci M, Elefante A, Strianese D, et al. Semiautomatic Regional Segmentation to Measure Orbital Fat Volumes in Thyroid-Associated Ophthalmopathy: A Validation Study. The neuroradiology journal. 2013;26(4):373–379. doi: 10.1177/197140091302600402
  8. Cai QY, Chen ZY, Jiang W, et al. A novel method for quantitative measurement of orbital fat volume based on magnetic resonance images. Nan Fang Yi Ke Da Xue Xue Bao. 2017;37(9):1248–1251. doi: 10.3969/j.issn.1673-4254.2017.09.18
  9. Shen J, Jiang W, Luo YS, et al. Establishment of MRI 3D Reconstruction Technology of Orbital Soft Tissue and Its Preliminary Application in Patients with Thyroid-Associated Ophthalmopathy. Clini Endocrinol. 2018;88(5):637–644. doi: 10.1111/cen.13564
  10. Sadovskaya OP, Dravitsa LV, Alkhadzh KAA. MRI diagnosis of orbital fat volume in patients with graves orbithopathy. Modern technologies in ophthalmology. 2020;(4):148–149. (In Russ.) doi: 10.25276/2312-4911-2020-4-148-149
  11. Shen J, Jiang W, Luo Y, et al. Establishment of magnetic resonance imaging 3D reconstruction technology of orbital soft tissue and its preliminary application in patients with thyroid-associated ophthalmopathy. Clin Endocrinol (Oxf). 2018;88(5):637–644. doi: 10.1111/cen.13564
  12. Yatsenko OYu. Volumetric, topographic and structural changes of orbital apex soft tissues in optic neuropathy caused by edematous exophthalmos. Ophthalmology in Russia. 2014;11(2):48–54. (In Russ.)
  13. Bontzos G, Mazonakis M, Papadaki E, et al. Ex vivo orbital volumetry using stereology and CT imaging: A comparison with manual planimetry. Eur Radiol. 2019;29(3):1365–1374. doi: 10.1007/s00330-018-5691-9
  14. Regensburg NI, Kok PH, Zonneveld FW, et al. A new and validated CT-based method for the calculation of orbital soft tissue volumes. Invest Ophthalmol Vis Sci. 2008;49(5):1758–1762. doi: 10.1167/iovs.07-1030
  15. Garau LM, Guerrieri D, De Cristofaro F, et al. Extraocular muscle sampled volume in Graves’ orbitopathy using 3-T fast spin-echo MRI with iterative decomposition of water and fat sequences. Acta Radiol Open. 2018;7(6):2058460118780892. doi: 10.1177/2058460118780892
  16. Brovkina AF, Yatsenko OYu, Aubakirova AS. Procedure for calculating the volume of the orbital fat to be removed at decompressive surgery in patients with endocrine ophthalmopathy. The Russian annals of ophthalmology. 2009;125(3):24–26. (In Russ.)
  17. Li B, Feng L, Tang H, et al. A new radiological measurement method used to evaluate the modified transconjunctival orbital fat decompression surgery. BMC Ophthalmol. 2021;21(1):176. doi: 10.1186/s12886-021-01911-9

Supplementary files

Supplementary Files
Action
1. JATS XML
2. Fig. 1. MSCT. 3D reconstruction in the bone mode. Placing a mark on the orbital seam of one of the orbits (arrow)

Download (106KB)
3. Fig. 2. MSCT. 3D reconstruction in the bone mode. Alignment of the frontal plane and removal of the data array located behind this plane

Download (40KB)
4. Fig. 3. MSCT. 3D reconstruction in soft tissue mode. Noted the zone of entry into the orbit along the bone edge, images outside the circle were excluded from the analysis

Download (61KB)
5. Fig. 4. MSCT. 3D reconstruction in soft tissue mode. Measurement of the magnitude of the exophthalmos of the right orbit (AB segment) before surgery and the estimated exophthalmos (AС segment) after surgery

Download (102KB)
6. Fig. 5. MSCT. 3D reconstruction in soft tissue mode. The amount of fatty tissue calculated using standard programs MSCT, which must be removed during surgery

Download (102KB)

Copyright (c) 2021 Konovalov K.A., Davydov D.V., Lezhnev D.A.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
 


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies