The influence of phacoemulsification on various corneal layers in patients with pseudoexfoliation syndrome assessed with confocal in vivo microscopy

Cover Page

Cite item

Full Text

Abstract

Phacoemulsification (PHACO) is the basic procedure of cataract extraction.

Purpose. To assess the impact of PHACO on corneal epithelium layers in patients with pseudoexfoliation syndrome (PEX) by confocal in vivo microscopy.

Methods. 24 patients with PEX syndrome and 18 patients without it were enrolled in the prospective study. In vivo confocal microscopy was performed with assessment of cellular density in corneal epithelial layers, degree of its desquamation, degree of Bowman membrane stiffening and dendritic cells density.

Results. The epithelial cells density didn’t change significantly in groups. Confocal microscopy showed high density of dendritic cells and marked desquamation of the epithelium in patients with PEX (p < 0,05) after PHACO.

About the authors

Vitaly V. Potemkin

Ophthalmologic Center of Saint Petersburg State Hospital No 2

Author for correspondence.
Email: potem@inbox.ru

Ophthalmologist

Russian Federation, Saint Petersburg

Tatyana S. Varganova

Ophthalmologic Center of Saint Petersburg State Hospital No 2

Email: varganova.ts@yandex.ru

Ophthalmologist

Russian Federation, Saint Petersburg

Irina V. Terekhova

Ophthalmologic Center of Saint Petersburg State Hospital No 2

Email: irterehova@yandex.ru

Chief of Ophthalmology diagnostic department

Russian Federation, Saint Petersburg

Elena V. Ageeva

Ophthalmologic Center of Saint Petersburg State Hospital No 2

Email: ageeva_elena@inbox.ru

Ophthalmologist

Russian Federation, Saint Petersburg

References

  1. Потёмкин В.В., Варганова Т.С., Акопов Е.Л., Агеева Е.В. Влияние псевдоэксфолиативного синдрома на морфологические свойства роговицы по данным конфокальной in vivo микроскопии // Офтальмологические ведомости. – 2017. – Т. 10. – № 2. – С. 49–55. [Potemkin VV, Varganova TS, Akopov EL, Ageeva EV. The influence of pseudoexfoliative syndrome on corneal morphology based on in vivo confocal microscopy. Ophthalmology Journal. 2017;10(2):49-55. (In Russ.)]. doi: 10.17816/OV10249-55.
  2. Потёмкин В.В., Агеева Е.В. Состояние глазной поверхности при псевдоэксфолиативном синдроме // Учёные записки СПбГМУ им. акад. И.П. Павлова. – 2016. – Т. 23. – № 1. – С. 47–50. [Potemkin VV, Ageeva EV. Ocular surface condition in patients with pseudoexfoliative syndrome. The Scientific Notes of the I.P. Pavlov St. Petersburg State Medical University. 2016;23(1):47-50. (In Russ.)]. doi: 10.24884/1607-4181-2016-23-1-47-50.
  3. Потёмкин В.В., Варганова Т.С., Агеева Е.В. Возможности конфокальной микроскопии при заболеваниях глазной поверхности // Офтальмологические ведомости. – 2017. – Т. 10. – № 1. – С. 23–30. [Potemkin VV, Varganova TS, Ageeva EV. Confocal microscopy in ocular surface disease. Ophthalmology Journal. 2017;10(1):23-30. (In Russ.)]. doi: 10.17816/OV1023-30.
  4. Потёмкин В.В., Агеева Е.В. Причины поражения тканей глазной поверхности при псевдоэксфолиативном синдроме // Российский офтальмологический журнал. – 2017. – Т. 10. – № 3. – С. 62–68. [Potemkin VV, Ageeva EV. Causes of ocular surface tissue lesions in patients with pseudoexfoliation syndrome. Russian Ophthalmological Journal. 2017;10(3):62-68. (In Russ.)]. doi: 10.21516/2072-0076-2017-10-3-62-68.
  5. Cetinkaya S, Mestan E, Acir NO, et al. The course of dry eye after phacoemulsification surgery. BMC Ophthalmol. 2015;15:68. doi: 10.1186/s12886-015-0058-3.
  6. Cho YK, Kim MS. Dry eye after cataract surgery and associated intraoperative risk factors. Korean J Ophthalmol. 2009;23:65-73. doi: 10.3341/kjo.2009.23.2.65.
  7. Erdogan H, Arici DS, Toker MI. Conjunctival impression cytology in pseudoexfoliative glaucoma and pseudoexfoliation syndrome. Clin Experim Ophthalmol. 2006;34:108-113. doi: 10.1111/j.1442-9071.2006.01168.x.
  8. Kocabeyoğlu S, İrkec M, Orhan M, Mocan M. Evaluation of the Ocular Surface Parameters in Pseudoexfoliation Syndrome and Conjunctivochalasis. Hacettepe University School of Medicine, Department of Ophthalmology, 2012.
  9. Laatikainen LР. Exfoliation syndrome and cataract extraction. Am J Ophthalmol. 1993.
  10. Naumann GH. Schlötzer-Schrehardt U. Corneal endothelial involvement in pseudoexfoliation syndrome. Arch Ophthalmol. 1994;112297-298. doi: 10.1001/archopht.1994.01090150027003.
  11. Naumann GO, Schlötzer-Schrehardt U. Keratopathy in pseudoexfoliation syndrome as a cause of corneal endothelial decompensation. A clinicopathologic study. Ophthalmology. 2000;107(6):1111-24. doi: 10.1016/S0161-6420(00)00087-7.
  12. Quiroga L, Lansingh VC, Samudio M, et al. Characteristics of the corneal endothelium and pseudoexfoliation syndrome in patients with senile cataract. Clin Experiment Ophthalmol. 2010;38(5):449-55. doi: 10.1111/j.1442-9071.2010.02313.x.
  13. Ritch R, Schlotzer-Schrehardt U. Exfoliation syndrome. Survey of Ophthalmology. 2001;45:265-313. doi: 10.1016/S0039-6257(00)00196-X.
  14. Schlötzer-Schrehardt U, Naumann GO. Ocular and systemic pseudoexfoliation syndrome. Am J Ophthalm. 2006:921-937.
  15. Summanen P, Tönjum AM. Exfoliation syndrome. Act Ophthalmol. 1998;184(Suppl.):107-111.
  16. Schlötzer-Schrehardt U, Koca M, Naumann G., Volkholz H. Pseudoexfoliation syndrome: ocular manifestation of a systemic disorder. Arch Ophthalmol. 1992;110:1752-1756.
  17. Schumacher S, Schlötzer-Schrehardt U, Martus P, et al. Pseudoexfoliation syndrome and aneurysms of the abdominal aorta. Lancet. 2001;357:359-360. doi: 10.1016/S0140-6736(00)03645-X.
  18. Sahu PK, Das GK, Malik A, Biakthangi L. Dry eye following phacoemulsification surgery and its relation to associated intraoperative risk factors. Middle East African Journal of Ophthalmology. 2015;22(4):472-477. doi: 10.4103/0974-9233.151871.
  19. Zheng X. New findings for an old disease: morphological studies on pseudoexfoliation syndrome-related keratopathy and binocular asymmetry. Cornea. 2013;(Nov;32 Suppl1):84-90.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2017 Potemkin V.V., Varganova T.S., Terekhova I.V., Ageeva E.V.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
 


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies