Efficacy of leucosapphire drainage implant use in IOP-lowering surgery in patients with refractory glaucoma

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Abstract

Aim. to evaluate the efficacy of leucosapphire explantodrainage implantation in IOP-lowering surgery in patients with refractory course of glaucoma.

Materials and methods. An analysis of surgical treatment results of 58 patients (60 eyes) with refractory glaucoma of different nature was performed. In 29 cases (29 eyes), at IOP-lowering procedure, a leucosapphire drainage was implanted. In 29 cases (31 eyes), standard deep sclerectomy was performed. We estimated immediate and long-term IOP-lowering and functional results of surgeries, as well as complication frequency and character. The follow-up of patients was from 1 to 8 years.

Results. In the first week after surgery, mean IOP after implantation of leucosapphire drainage decreased from 32.4 ± 0.7 to 14.8 ± 1.0 mm Hg (by Maklakov 10 g tonometry), and from 30.8 ± 0.9 to 16.4 ± 1.0 mm Hg after deep sclerectomy. After 12 months, mean IOP was 20.5 ± 0.9 mm Hg and 24.6 ± 1.2 mm Hg in patients who underwent leucosapphire drainage implantation and deep sclerectomy, respectively. By that time, IOP was stabilized in 89.6% of cases after leucosapphire drainage implantation (in 37.9% – without additional therapy) and in 61.3% (16.1% without additional therapy) – after deep sclerectomy. Perimetry data were ameliorated or stabilized in 69.0% of cases after implantation of leucosapphire drainage and in 48.3% – after deep sclerectomy.

Conclusion. The implantation of leucosapphire drainage device is an effective treatment method for patients with refractory glaucoma forms. It provides better IOP control in the late postoperative period in comparison with a traditional technique of glaucoma surgery. The frequency and character of complications were comparable in both groups.

About the authors

Vladimir V Naumenko

Saint Petersburg branch of S. Fyodorov Eye Microsurgery Federal State Institution

Author for correspondence.
Email: naumencko083@yandex.ru

MD, head of science and education department

Russian Federation, Saint Petersburg, Russia

Marina M Pravosudova

Saint Petersburg branch of S. Fyodorov Eye Microsurgery Federal State Institution

Email: marprav@front.ru

ophthalmologist

Russian Federation, Saint Petersburg, Russia

Marina A Kladko

North-western State Medical University named after I.I. Mechnikov

Email: thedoveofpeace@mail.ru

resident

Russian Federation, Saint Petersburg, Russia

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Copyright (c) 2017 Naumenko V.V., Pravosudova M.M., Kladko M.A.

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