不同的手术矫正人工晶状体脱位方法对角膜内 皮的影响

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引言: 人工晶状体（IOL）脱位是白内障患者手术治疗中罕见但相当严重的并发症。假性剥脱综合征（PEX）、轴性高度近视、慢性葡萄膜炎、外伤史和年龄被认为是主要诱因。目前还没有矫正IOL脱位的通用技术。

目的: 评估两种不同的手术矫正IOL脱位技术即：经巩膜缝合固定IOL复位和植入虹膜夹型IOL(iris-clow-IOL)替换IOL对角膜内皮的影响。

材料和方法: 在该研究中78名患者进行了检查和手术。所有患者被分为两组：第一组接受经巩膜缝合固定IOL复位；第二组接受植入虹膜夹型IOL(iris-clow-IOL)替换IOL。这两组患者的性别和年龄都相同。主要评估参数是反映多形性程度的内皮细胞密度和变异系数。

结果: 植入虹膜夹型IOL(iris-clow-IOL)替换IOL组术前和术后内皮细胞数量都显著降低。在整个研究过程中，该组的变异系数更高，内皮细胞丢失的百分比明显更高。

结论: IOL脱位治疗方法的选择是手术矫正成功的核心，必须考虑术前的检查数据，即脱位程度、IOL型号、眼压水平、内皮细胞数量以及是否伴随眼部疾病。

作者简介

Vitaly V. Potyomkin

Pavlov First St. Petersburg State Medical University; City Multidiscipline Hospital No. 2

Email: potem@inbox.ru
ORCID iD: 0000-0001-7807-9036

Cand. Sci. (Med.)

俄罗斯联邦, 6–8 L’va Tolstogo str., Saint Petersburg, 197022; 5 Uchebniy pereulok, Saint Petersburg, 194354

Sergey Yu. Astakhov

Pavlov First St. Petersburg State Medical University

Email: astakhov73@mail.ru
ORCID iD: 0000-0003-0777-4861
SPIN 代码: 7732-1150

MD, PhD, Dr. Sci. (Med.), Professor

俄罗斯联邦, 6–8 L’va Tolstogo str., Saint Petersburg, 197022

Elena V. Goltsman

City Multidiscipline Hospital No. 2

Email: ageeva_elena@inbox.ru
ORCID iD: 0000-0002-2568-9305

ophthalmologist

俄罗斯联邦, 5 Uchebniy pereulok, Saint Petersburg, 194354

Xiaoyuan Wang

Pavlov First St. Petersburg State Medical University

Email: wangxiaoyuan20121017@gmail.com

PhD student

俄罗斯联邦, 6–8 L’va Tolstogo str., Saint Petersburg, 197022

Yulduz Sh. Nizametdinova

City Multidiscipline Hospital No. 2

编辑信件的主要联系方式.
Email: yulduzik55@gmail.com
ORCID iD: 0000-0002-6789-5780
SPIN 代码: 7482-5163

ophthalmic surgeon

俄罗斯联邦, 5 Uchebniy pereulok, Saint Petersburg, 194354

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补充文件

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2. 图.5.患者术前（a）和术后3个月（b）的角膜裂隙灯检查 Fig. 5. Biomicroscopy of the patient’s cornea before (а) and 3 months (b) after surgery

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3. 图.1.角膜缘小袋形成 Fig. 1. Formation of limbal mini-pockets

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4. 图.2.将IOL固定在巩膜上 Fig. 2. IOL fixation to the sclera

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5. 图.3.注入针巩膜内走向 Fig. 3. Intrascleral pass of the needle

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6. 图.4.术后1年各组的内皮细胞密度 Fig. 4. Endothelial cell density in groups within 1 year

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版权所有 © Potyomkin V., Astakhov S., Goltsman E., Wang X., Nizametdinova Y., 2021

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