Email this article 
Post a Comment Comparative evaluation of the results of surgical treatment of open-angle glaucoma using an Ex-Press® P-200 filtration device and drainage device “anti-glaucoma implant A3”
- Authors: Grineva M.K.1, Astakhov S.Y.1, Turgel V.A.2
-
Affiliations:
- Academican I.P. Pavlov First St. Petersburg State Medical University of the Ministry of Healthcare of the Russian Federation
- I.P. Pavlov First St. Petersburg State Medical University
- Issue: Vol 13, No 3 (2020)
- Pages: 29-36
- Section: Original researches
- URL: https://journals.rcsi.science/ov/article/view/42464
- DOI: https://doi.org/10.17816/OV42464
- ID: 42464
Cite item
Open Access
Access granted
Subscription Access
Abstract
Purpose. The article presents the results of a comparative analysis of the effectiveness of surgical treatment of open-angle glaucoma using the Ex-Press® P-200 filtering device and the “Anti-glaucoma A3 implant”.
Materials and methods. Using simple sequential sampling, 52 patients (59 eyes) were divided into 2 groups. The first group was implanted with Ex-Press® P-200, the second – with “Anti-glaucoma implant A3”. The follow-up period for patients ranged from 6 months to three years. At each visit, a standard ophthalmic examination was performed. For tonometry, the ICare TA01i portable non-contact tonometer was used. To assess the stabilization of the glaucoma process, we performed static (threshold) automatic perimetry using the Pericom perimeter and optical coherence tomography (OCT) of the optic nerve heads using a Spectralis HRA-OCT tomograph (Heidelberg Engineering).
Conclusions. The implantation of devices of both types led to a persistent decrease in intraocular pressure, maintenance of visual functions, and stabilization of the glaucoma process. Intra- and postoperative complications corresponded to the nature of filtering procedures and did not have significant differences in the groups. However, cases of shunt erosion were noted only in the group with implanted Ex-Press® devices.
Full Text
##article.viewOnOriginalSite##About the authors
Maria K. Grineva
Academican I.P. Pavlov First St. Petersburg State Medical University of the Ministry of Healthcare of the Russian Federation
Author for correspondence.
Email: mariagrineva83@gmail.com
ORCID iD: 0000-0003-1279-7996
SPIN-code: 4547-9835
ResearcherId: D-8824-2019
Postgraduate, Ophthalmology Department
Russian Federation, Saint PetersburgSergey Yu. Astakhov
Academican I.P. Pavlov First St. Petersburg State Medical University of the Ministry of Healthcare of the Russian Federation
Email: astakhov73@mail.ru
SPIN-code: 7732-1150
Scopus Author ID: 56660518500
MD, PhD, DMedSc, Professor, Head of the Ophthalmology Department
Russian Federation, Saint PetersburgVadim A. Turgel
I.P. Pavlov First St. Petersburg State Medical University
Email: Zanoza194@gmail.com
Resident, Department of Ophthalmology
Russian Federation, Saint PetersburgReferences
- Измайлова С.Б. Хирургическое лечение основных форм глаукомы с использованием гидрогелевого дренажа в проникающей хирургии малых разрезов: Афтореф. дис. … канд. мед. наук. – М., 2005. – 24 с. [Izmailova SB. Khirurgicheskoe lechenie osnovnykh form glaukomy s ispol’zovaniem gidrogelevogo drenazha v pronikayushchei khirurgii malykh razrezov. [dissertation abstract] Moscow; 2005. 24 р. (In Russ.)]
- Еричев В.П., Слепова О.С., Ловпаче Д.Н. Цитокиновый скрининг при первичной открытоугольной и вторичной постувеальной глаукоме как иммунологическое прогнозирование избыточного рубцевания после антиглаукоматозных операций // Глаукома. – 2001. – № 1. – С. 11–16. [Erichev VP, Slepova OS, Lovpache DN. Tsitokinovyi skrining pri pervichnoi otkrytougol’noi i vtorichnoi postuveal’noi glaukome kak immunologicheskoe prognozirovanie izbytochnogo rubtsevaniya posle antiglaukomatoznykh operatsii. Glaucoma. 2001;(1):11-16. (In Russ.)]
- Заболотный А.Г., Мисакьян К.С., Бронская А.Н., и др. Методологические аспекты и анализ неэффективности применения мягких имплантов в дренажной непроникающей хирургии первичной и ранее оперированной открытоугольной глаукомы I–III стадий // Вестник Оренбургского государственного университета. – 2015. – № 12. – С. 72–75. [Zabolotniy AG, Misakiyan KS, Bronskaya AN, et al. Methodological aspects and analysis of the ineffectiveness of the implant in the soft drain primarypenetrating surgery before operated open angle glaucoma stage I–III. Vestnik of the Orenburg state university. 2015;(12):72-75. (In Russ.)]
- Даниличев В.Ф. Патология глаз. Ферменты и ингибиторы. – СПб.: Стройлеспечать, 1996. – 235 с. [Danilichev VF. Ophthalmic pathology. Enzymes and inhibitors. Saint Petersburg: Stroilespechat’; 1996. 235 р. (In Russ.)]
- Иванова Е.С. Применение цитостатиков в хирургии глаукомы // Перспективные направления в хирургическом лечении глаукомы: сб. науч. ст. / Под ред. С.Н. Федорова. – М.: МНТК «Микрохирургия глаза», 1997. – С. 43–46. [Ivanova ES. Primenenie tsitostatikov v khirurgii glaukomy. In: Perspektivnye napravleniya v khirurgicheskom lechenii glaukomy: sb. nauch. st. Ed. by S.N. Fedorov. Moscow: MNTK “Mikrokhirurgiya glaza”; 1997. Р. 43-46. (In Russ.)]
- Асратян Г.К. Разработка дифференцированного подхода к дренажной хирургии первичной открытоугольной глаукомы: Автореф. дис. … канд. мед. наук. – М., 2015. – 24 с. [Asratyan GK. Razrabotka differentsirovannogo podkhoda k drenazhnoi khirurgii pervichnoi otkrytougol’noi glaukomy. [dissertation abstract] Moscow; 2015. 24 р. (In Russ.)]
- Харша А.А. Сравнительная оценка эффективности оперативного лечения больных рефрактерной глаукомой с использованием клапана Ahmed™ и шунта EX-PRESS®: Автореф. дис. … канд. мед. наук. – СПб., 2014. – 15 с. [Kharsha AA. Sravnitel’naya otsenka ehffektivnosti operativnogo lecheniya bol’nykh refrakternoi glaukomoi s ispol’zovaniem klapana Ahmed™ i shunta EX-PRESS®. [dissertation abstract] Saint Petersburg; 2014. 15 р. (In Russ.)]
- World Health Organization. Visual impairment and blindness: fact sheet No 282. WHO; 2014. Available from: https://web.archive.org/web/20150512062236/http://www.who.int/mediacentre/factsheets/fs282/en/.
- Quigley HA, Broman AT. The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol. 2006;90(3): 262-267. https://doi.org/10.1136/bjo.2005.081224.
- Tham YC, Li X, Wong TY, et al. Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. Ophthalmology. 2014;121(11):2081-2090. https://doi.org/10.1016/j.ophtha.2014.05.013.
- Quigley HA. Glaucoma. Lancet. 2011;377(9774):1367-1377. https://doi.org/10.1016/S0140-6736(10)61423-7.
Supplementary files
