Ophthalmic manifestations of cytomegalovirus infection in HIV (literature review)

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Abstract

Cytomegalovirus (CMV) contamination is very common: in several countries, the number of seropositive people reaches 90% among the adult population. It is a latent infection able to affect any human organs and tissues that assumes special importance in severe immunosuppression cases. Cytomegalovirus retinitis is a disabling disease, and often leads to blindness. The article deals with some issues of epidemiology, clinical course, clinical presentation characteristics of cytomegalovirus eye disease in the context of HIV-infection. A special attention is given to detection methods, problems of diagnosis against the background of immune reconstruction syndrome, treatment approaches in clinical practice, and existing recommendations.

About the authors

Natalia G. Zumbulidze

North-Western State Medical University named after I.I. Mechnikov

Author for correspondence.
Email: guramovna@gmail.com
SPIN-code: 4439-8855

PhD, Assistent Professor of the Department of Ophthalmology

Russian Federation, Saint Petersburg

Tatyana D. Sizova

Saint Petersburg Center for Control of AIDS and Infectious Diseases

Email: tsizova25@gmail.com

Ophthalmologist

Russian Federation, Saint Petersburg

Valentina M. Khokkanen

North-Western State Medical University named after I.I. Mechnikov

Email: valentina.khokkanen@szgmu.ru

MD, Professor, Department of Ophthalmology

Russian Federation, Saint Petersburg

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Copyright (c) 2019 Zumbulidze N.G., Sizova T.D., Khokkanen V.M.

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This work is licensed under a Creative Commons Attribution 4.0 International License.
 


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