Effectiveness of repeated courses of specific hyposensitization in pollinosis

As we know, specific hypersensitization with pollen allergens is the most effective method of pollen allergy treatment. Such treatment is provided during remission period of pollen allergy (mostly in winter), and more often in separate courses. However, until now there is no consensus on the dependence of the effectiveness of specific treatment on the number of hypersensitization courses. The allergologist constantly faces the question of how long to conduct specific therapy, how many courses of hypersensitization can be considered sufficient for a particular patient. As a rule, this question has to be solved during the remission period of the disease, which causes great difficulties, since there are no objective criteria for the advisability of prescribing another course of treatment. Besides clinical peculiarities of pollen allergy the duration of a course of treatment probably depends on regional factors, first of all on climatic and geographic ones; therefore, the number of hypersensitization courses may be different in different regions of our country.