Humoral and cellular immunity parameters in rheumatoid arthritis patients

The leading role in the pathogenesis of rheumatoid arthritis belongs to the immunocomplex lesion with pronounced humoral and cellular reactions [7]. That is why a comprehensive study of the state of the humoral link of immunity and cellular reactions of the body is of particular interest in terms of both assessment of immune status and determination of the activity of the process, variants of the course of rheumatoid arthritis and the choice of adequate therapy. One of the main manifestations of immune disorders in rheumatoid arthritis is the formation of rheumatoid factor, detected in the blood of patients. Most authors consider its titer to be an important criterion for the diagnosis of the disease and the nature of the clinical course.