On the determination of the activity of rheumatism by the concentration of sialic acid in the blood serum in children

Determination of the activity of rheumatism does not cease to interest practical doctors, despite the large number of methods proposed for this purpose. Along with the ROE that has become firmly established in clinical practice, a number of very sensitive laboratory methods for determining the activity of the rheumatic process have recently been proposed. One of them is the determination of C-reactive protein in blood serum, which disappears much earlier than ROE normalization (A.I. Vorobyova, A.P. Sleptsov, etc.). An increase in the amount of fibrin in plasma is also characteristic of the acute phase of rheumatism; the highest rates were observed in rheumatic polyarthritis, but with the subsidence of the activity of rheumatism, a rapid decrease to normal values ​​is observed, similar to the reaction to C-reactive protein (A.I. Vorobieva).